Fecal microbiota relationships with childhood obesity: A scoping comprehensive review

被引:21
作者
de Cuevillas, Begona [1 ]
Milagro, Fermin I. [1 ,2 ,3 ]
Tur, Josep A. [2 ,4 ,5 ]
Gil-Campos, Mercedes [2 ,6 ]
de Miguel-Etayo, Pilar [2 ,7 ]
Martinez, J. Alfredo [1 ,2 ,3 ,8 ]
Navas-Carretero, Santiago [1 ,2 ,3 ]
机构
[1] Univ Navarra, Sch Pharm & Nutr, Dept Nutr Food Sci & Physiol, Ctr Nutr Res, Pamplona, Spain
[2] Inst Salud Carlos III, Ctr Invest Biomed Red Fisiopatol Obesidad & Nutr, Madrid, Spain
[3] Hlth Res Inst Navarra, IdiSNA, Pamplona, Spain
[4] Univ Balearic Islands IUNICS, Res Grp Community Nutr & Oxidat Stress, Palma de Mallorca, Spain
[5] IDISBA, Palma de Mallorca, Spain
[6] Univ Cordoba, Reina Sofia Univ Hosp, Maimonides Inst Biomed Res Cordoba IMIBIC, Metab & Invest Unit, Cordoba, Spain
[7] Univ Zaragoza, Inst Agroalimentario Arag IA2, Inst Invest Sanitaria Aragon IIS Aragon, Growth Exercise Nutr & Dev GENUD Res Grp, Zaragoza, Spain
[8] CSIC UAM, Precis Nutr Program, Res Inst Food & Hlth Sci IMDEA Food, Madrid, Spain
关键词
childhood obesity; dysbiosis; microbiota; STOP project; ALTERED GUT MICROBIOTA; INTESTINAL MICROBIOTA; HUMAN-MILK; PEDIATRIC OBESITY; INFANT MICROBIOME; IMPACT; RISK; OLIGOSACCHARIDES; CHILDREN; EXPOSURE;
D O I
10.1111/obr.13394
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Childhood obesity is a costly burden in most regions with relevant and adverse long-term health consequences in adult life. Several studies have associated excessive body weight with a specific profile of gut microbiota. Different factors related to fecal microorganism abundance seem to contribute to childhood obesity, such as gestational weight gain, perinatal diet, antibiotic administration to the mother and/or child, birth delivery, and feeding patterns, among others. This review reports and discusses diverse factors that affect the infant intestinal microbiota with putative or possible implications on the increase of the obesity childhood rates as well as microbiota shifts associated with excessive body weight in children.
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页数:14
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