Dendrimers and their supramolecular nanostructures for biomedical applications

被引:30
作者
Selin, Markus [1 ]
Peltonen, Leena [1 ]
Hirvonen, Jouni [1 ]
Bimbo, Luis M. [1 ]
机构
[1] Univ Helsinki, Fac Pharm, Div Pharmaceut Chem & Technol, POB 56 Viikinkaari 5E, FI-00014 Helsinki, Finland
基金
芬兰科学院;
关键词
(Janus) dendrimers; Dendrons; Hydrogels; Nanostructures; Polymers; Supramolecular structures; DENDRITIC DIPEPTIDES; PEPTIDE-AMPHIPHILES; HYALURONIC-ACID; CITRIC-ACID; HYBRID GELS; HYDROGEL; DELIVERY; DENDRONS; MICELLE; RELEASE;
D O I
10.1016/j.jddst.2016.02.008
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Pharmaceutical nanotechnology is the field of materials science that focuses on techniques to process raw materials to produce nanostructures with desired properties for pharmaceutical applications. Nanostructures can be roughly divided into surface textures, tubular structures or particles, depending on how many of their dimensions are on the nanoscale. The structures may also be divided into hard and soft structures, depending on their physical properties. There has been lately a growing interest to study soft supramolecular structures. In this review, the main focus is to briefly introduce the reader to various aspects of dendrimers, including Janus dendrimers, and supramolecular structures and then focus on recent studies dealing with application of dendrimer-based supramolecular structures in the pharmaceutical field. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:10 / 20
页数:11
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