Metastatic placental site trophoblastic tumor - Report of a case with complete response to chemotherapy

被引:0
作者
Mangili, G
Garavaglia, E
De Marzi, P
Zanetto, F
Taccagni, C
机构
[1] Osped San Raffaele, Dept Obstet & Gynecol, I-20100 Milan, Italy
[2] Osped San Raffaele, Dept Pathol, I-20100 Milan, Italy
关键词
placental-site trophoblastic tumor; metastasis; combination chemotherapy;
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
BACKGROUND: Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic neoplasia, commonly insensitive to chemotherapeutic agents. CASE: We report on longterm remission in a patient with metastatic PSTT after etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine combination chemotherapy. The 27-year-old patient with metastatic lung PSTT was alive, without evidence of disease, >40 months after treatment. CONCLUSION: Treatment with multiagent chemotherapy can produce long-term remission, even in patients with metastatic PSTT.
引用
收藏
页码:259 / 262
页数:4
相关论文
共 50 条
[31]   Coexisting epithelioid trophoblastic tumor and placental site trophoblastic tumor of the uterus following a term pregnancy: report of a case and review of literature [J].
Zhang, Xiaofei ;
Zhou, Caiyun ;
Yu, Minghua ;
Chen, Xiaoduan .
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 8 (06) :7254-7259
[32]   Diagnosis and management of a rare case with placental site trophoblastic tumor [J].
Cho, Fu-Nan ;
Chen, San-Nung ;
Chang, Yu-Hsiang ;
Carey, James R. .
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2016, 55 (05) :724-727
[33]   A case of transient hyperthyroidism induced by placental site trophoblastic tumor [J].
Ishii, Sumire ;
Hirayama, Takashi ;
Saeki, Harumi ;
Fujino, Kazunari ;
Terao, Yasuhisa ;
Itakura, Atsuo .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2025, 51 (01)
[34]   Placental site trophoblastic tumor - An overview [J].
Bonazzi, C ;
Urso, M ;
Dell'Anna, T ;
Sacco, S ;
Buda, A ;
Cantu, MG .
JOURNAL OF REPRODUCTIVE MEDICINE, 2004, 49 (08) :585-588
[35]   Placental site trophoblastic tumor of the mediastinum [J].
Went, PT ;
Dirnhofer, S ;
Stallmach, T ;
Taverna, C ;
Singer, G .
HUMAN PATHOLOGY, 2005, 36 (05) :581-584
[36]   Successful management of metastatic placental site trophoblastic tumor with multiple pulmonary resections [J].
Carlson, N ;
Winter, WE ;
Krivak, TC ;
Crothers, B ;
Macri, C ;
Carlson, JW .
GYNECOLOGIC ONCOLOGY, 2002, 87 (01) :146-149
[37]   Placental site trophoblastic tumor presented with vaginal metastasis [J].
Zhang, Hai-Yan ;
Yue, Xiao-Ni ;
Tao, Xiang ;
Xi, Mei-Li ;
Yan, An-Qi ;
Lu, Xin .
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2015, 8 (02) :2993-2997
[38]   Placental Site Trophoblastic Tumor with Ambiguous Radiological Features; An Interesting Case Report with Review of Literature [J].
Bhoomika Kaushik ;
Rakesh Kumar Gupta ;
Sarita Agrawal ;
Amit Kumar .
SN Comprehensive Clinical Medicine, 7 (1)
[39]   Trophoblastic gestational disease:: a placental site trophoblastic tumor and an epithelioid trophoblastic [J].
Bouchet-Mishellany, F ;
Ledoux-Pilon, A ;
Darcha, C ;
Déhelotte, P .
ANNALES DE PATHOLOGIE, 2004, 24 (02) :167-171
[40]   PLACENTAL SITE TROPHOBLASTIC TUMOR - REPORT OF 3 CASES AND REVIEW OF THE LITERATURE [J].
HOW, J ;
SCURRY, J ;
GRANT, P ;
SAPOUNTZIS, K ;
OSTOR, A ;
FORTUNE, D ;
ARMES, J .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 1995, 5 (04) :241-249