Continuous-Flow Synthesis of 5-Hydroxymethylfurfural, Furfural from Monosaccharides: A Simple, Fast, and Practical Method

被引：16

作者：

Phat Duc Ly ^{[1
,2
]}

Ha Bich Phan ^{[1
,2
,3
]}

Yen-Nhi Thi Le ^{[1
,2
]}

Phuong Hoang Tran ^{[1
,2
]}

机构：

[1] Univ Sci, Fac Chem, Dept Organ Chem, Ho Chi Minh City, Vietnam

[2] Vietnam Natl Univ, Ho Chi Minh City, Vietnam

[3] Inst Publ Hlth, Ho Chi Minh City, Vietnam

来源：

CHEMISTRYSELECT | 2021年 / 6卷 / 40期

关键词：

5-Hydroxymethylfurfural; fructose; continuous-flow synthesis; p-TsOH; Bronsted acidic ionic liquids; LIQUID BINARY-MIXTURES; CATALYTIC CONVERSION; CARBOHYDRATE CONVERSION; FRUCTOSE DEHYDRATION; ACID CATALYST; EFFICIENT; CELLULOSE; BIOMASS; COMBINATION; MONOMERS;

D O I：

10.1002/slct.202102841

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5-Hydroxymethylfurfural (HMF), a versatile intermediate from biomass, can be applied to prepare a wide range of valuable compounds in the petroleum and chemical industries. Thus, simple, fast, and practical methods to convert carbohydrates into HMF have been capturing increasing attention. We reported herein a method of using p-toluenesulfonic acid (p-TsOH) and Bronsted acidic ionic liquid as catalysts for the dehydration of fructose in dimethyl sulfoxide (DMSO) under a continuous flow process. The effect of the various reaction conditions on HMF formation was investigated, and the HMF yields were determined by the HPLC method. The results showed that p-TsOH and Bronsted acidic ionic liquid are effective catalysts within short residence times. This study provides a simple and safe procedure that can be potentially performed on a large scale to synthesize HMF from fructose.

引用

页码：10827 / 10833

页数：7

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