Liquid chromatographic separation of chiral triazolophthalazines

被引:4
|
作者
Stelzer, A
Jira, T
Meusel, M
Morgenstern, O
Plumer, F
机构
[1] UNIV GREIFSWALD,INST DRUG CONTROL,D-17489 GREIFSWALD,GERMANY
[2] UNIV GREIFSWALD,INST PHARMACEUT CHEM,D-17489 GREIFSWALD,GERMANY
关键词
enantiomer separation; chiral stationary phases; LC; triazolophthalazines;
D O I
10.1016/0021-9673(96)00007-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Investigations of the synthesis of N,N-linked heterobicyclic compounds, synthesized with cyclic hydrazine derivatives, have been the focus of the authors' research for some time. Using carbonyl compounds, the synthesis of chiral triazolophthalazines and thiadiazolophthalazines was recently achieved. The chromatographic investigation of these newly synthesized triazolophthalazines was of great interest. Different results were obtained with different chiral stationary phases. The influence of temperature and mobile phase composition was investigated.
引用
收藏
页码:5 / 11
页数:7
相关论文
共 50 条