Phytochemical constituents and antimicrobial activity from the stems of Jatropha maheshwarii

被引：8
作者：
Viswanathan, MB [1 ]
Ramesh, N
Ahilan, A
Lakshmanaperumalsamy, P
机构：
[1] Manonmaniam Sundaranar Univ, Sir Paramakalyani Ctr Environm Sci, Div Biodivers & Drug Dev, Alwarkurichi 627412, Tamil Nadu, India
[2] Sri Kaliswari Coll, Dept Biotechnol, Sivakasi 626130, Tamil Nadu, India
[3] Ponnaiyah Ramajayam Coll, Dept Biotechnol, Thanjavur 614904, Tamil Nadu, India
[4] Bharathiar Univ, Dept Environm Sci, Coimbatore 641046, Tamil Nadu, India
来源：
MEDICINAL CHEMISTRY RESEARCH | 2004年 / 13卷 / 6-7期
关键词：
Jatropha maheshwarii; Euphorbiaceae; stem; aqueous and solvent extracts; antimicrobial activity;
D O I：
10.1007/s00044-004-0041-7
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Isolation of the natural products from the stems of Jatropha maheshwarii yielded 5 compounds such as Friedelin (0.16%), epi-friedelinol (0.12%), n-octacosanol (0.11%), beta-sitosterol (0.2%), and beta-sitosterol-3-beta-D-glucopyranoside (0.24%). Aqueous and organic solvent extracts tested by agar-well diffusion method against 12 human pathogenic bacteria and 3 fungal strains showed activity to most of the organisms. Methanol extract exhibited maximum activity. Activity against S. aureus provides scientific evidence for use in skin diseases and toothaches.
引用
收藏
页码：361 / 368
页数：8
相关论文
共 50 条
  • [1] ABDUAGUYE I, 1986, BRIT J CLIN PHARMACO, V21, pP585
  • [2] ADEWUNMI CO, 1986, FITOTERAPIA, V7, P353
  • [3] AGUYE A, 1985, HUMAN TOXICOLOGY, V5, P269
  • [4] Aiyelaagbe OO, 2000, PHYTOTHER RES, V14, P60, DOI 10.1002/(SICI)1099-1573(200002)14:1&lt
  • [5] 60::AID-PTR597&gt
  • [6] 3.0.CO
  • [7] 2-B
  • [8] Antibacterial activity of Jatropha multifida roots
    Aiyelaagbe, OO
    [J]. FITOTERAPIA, 2001, 72 (05) : 544 - 546
  • [9] ANTIMICROBIAL ACTIVITIES OF CRUDE LEAF EXTRACTS OF ACALYPHA-WILKESIANA
    ALADE, PI
    IROBI, ON
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 1993, 39 (03) : 171 - 174
  • [10] ASTHANA A, 1989, International Journal of Crude Drug Research, V27, P25
12345