The effect of anodal transcranial direct current stimulation over the primary motor or somatosensory cortices on somatosensory evoked magnetic fields

被引：15
作者：
Sugawara, Kazuhiro [1 ]
Onishi, Hideaki [1 ]
Yamashiro, Koya [1 ]
Kojima, Sho [1 ]
Miyaguchi, Shota [1 ]
Kirimoto, Hikari [1 ]
Tsubaki, Atsuhiro [1 ]
Tamaki, Hiroyuki [1 ]
Shirozu, Hiroshi [2 ]
Kameyama, Shigeki [2 ]
机构：
[1] Niigata Univ Hlth & Welf, Inst Human Movement & Med Sci, Kita Ku, Niigata 9503198, Japan
[2] Nishi Niigata Chuo Natl Hosp, Dept Neurosurg, Nishi Ku, Niigata 9502085, Japan
来源：
CLINICAL NEUROPHYSIOLOGY | 2015年 / 126卷 / 01期
基金：
日本学术振兴会;
关键词：
Transcranial direct current stimulation; Somatosensory evoked magnetic fields; Primary motor cortex; Primary somatosensory cortex; Magnetoencephalography; Median nerve stimulation; MEDIAN NERVE-STIMULATION; PRIMARY SENSORIMOTOR CORTEX; PARIETAL CORTEX; EXCITABILITY; POTENTIALS; RESPONSES; HUMANS; MODULATION; MEG; MOVEMENT;
D O I：
10.1016/j.clinph.2014.04.014
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Objectives: The purpose of this study was to investigate the effect of anodal transcranial direct-current stimulation (tDCS) applied over the primary motor (M1) or the primary somatosensory (S1) cortices on somatosensory evoked magnetic fields (SEFs) following median nerve stimulation. Methods: Anodal tDCS was applied for 15 min on the left motor or somatosensory cortices at 1 mA. SEFs were recorded following right median nerve stimulation using a magnetoencephalography (MEG) system before and after the application of tDCS. SEFs was measured and compared before and after tDCS was applied over M1 or S1. Results: The source strengths for the P35m and P60m increased after tDCS was applied over M1 and that for the P60m increased after tDCS was applied over S1. The mean equivalent current dipole (ECD) location for the P35m was located significantly anterior to that of the N20m, but only during post 1 (10-20 min after tDCS was applied over M1). Conclusion: Our results indicated that the anodal tDCS applied over M1 affected the P35m and P60m sources on SEF components, while that applied over S1 influenced the P60m source. Significance: We demonstrated anodal tDCS applied over M1 or S1 can modulate somatosensory processing and components of SEFs, confirming the hypothesis for locally distinct generators of the P35m and P60m sources. (C) 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：60 / 67
页数：8
相关论文
共 45 条
  • [21] The somatosensory evoked magnetic fields
    Kakigi, R
    Hoshiyama, M
    Shimojo, M
    Naka, D
    Yamasaki, H
    Watanabe, S
    Xiang, J
    Maeda, K
    Lam, K
    Itomi, K
    Nakamura, A
    [J]. PROGRESS IN NEUROBIOLOGY, 2000, 61 (05) : 495 - 523
  • [22] Neuromagnetic evidence of pre- and post-central cortical sources of somatosensory evoked responses
    Kawamura, T
    Nakasato, N
    Seki, K
    Kanno, A
    Fujita, S
    Fujiwara, S
    Yoshimoto, T
    [J]. EVOKED POTENTIALS-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1996, 100 (01): : 44 - 50
  • [23] Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human
    Kincses, TZ
    Antal, A
    Nitsche, MA
    Bártfai, O
    Paulus, W
    [J]. NEUROPSYCHOLOGIA, 2004, 42 (01) : 113 - 117
  • [24] Transcranial direct current stimulation over the motor association cortex induces plastic changes in ipsilateral primary motor and somatosensory cortices
    Kirimoto, Hikari
    Ogata, Katsuya
    Onishi, Hideaki
    Oyama, Mineo
    Goto, Yoshinobu
    Tobimatsu, Shozo
    [J]. CLINICAL NEUROPHYSIOLOGY, 2011, 122 (04) : 777 - 783
  • [25] Enlarged SI and SII somatosensory evoked responses in the CLN5 form of neuronal ceroid lipofuscinosis
    Lauronen, L
    Huttunen, J
    Kirveskari, E
    Wikström, H
    Sainio, K
    Autti, T
    Santavuori, P
    [J]. CLINICAL NEUROPHYSIOLOGY, 2002, 113 (09) : 1491 - 1500
  • [26] Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability
    Liebetanz, D
    Nitsche, MA
    Tergau, F
    Paulus, W
    [J]. BRAIN, 2002, 125 : 2238 - 2247
  • [27] Differential generators for N20m and P35m responses to median nerve stimulation
    Lin, YY
    Chen, WT
    Liao, KK
    Yeh, TC
    Wu, ZA
    Ho, LT
    Lee, LS
    [J]. NEUROIMAGE, 2005, 25 (04) : 1090 - 1099
  • [28] Effect of transcranial DC sensorimotor cortex stimulation on somatosensory evoked potentials in humans
    Matsunaga, K
    Nitsche, MA
    Tsuji, S
    Rothwell, JC
    [J]. CLINICAL NEUROPHYSIOLOGY, 2004, 115 (02) : 456 - 460
  • [29] Corticomotor excitability induced by anodal transcranial direct current stimulation with and without non-exhaustive movement
    Miyaguchi, Shota
    Onishi, Hideaki
    Kojima, Sho
    Sugawara, Kazuhiro
    Tsubaki, Atsuhiro
    Kirimoto, Hikari
    Tamaki, Hiroyuki
    Yamamoto, Noriaki
    [J]. BRAIN RESEARCH, 2013, 1529 : 83 - 91
  • [30] Shaping the effects of transcranial direct current stimulation of the human motor cortex
    Nitsche, M. A.
    Doemkes, S.
    Karakose, T.
    Antal, A.
    Liebetanz, D.
    Lang, N.
    Tergau, F.
    Paulus, W.
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 2007, 97 (04) : 3109 - 3117
12345