The effect of anodal transcranial direct current stimulation over the primary motor or somatosensory cortices on somatosensory evoked magnetic fields

被引：15
作者：
Sugawara, Kazuhiro [1 ]
Onishi, Hideaki [1 ]
Yamashiro, Koya [1 ]
Kojima, Sho [1 ]
Miyaguchi, Shota [1 ]
Kirimoto, Hikari [1 ]
Tsubaki, Atsuhiro [1 ]
Tamaki, Hiroyuki [1 ]
Shirozu, Hiroshi [2 ]
Kameyama, Shigeki [2 ]
机构：
[1] Niigata Univ Hlth & Welf, Inst Human Movement & Med Sci, Kita Ku, Niigata 9503198, Japan
[2] Nishi Niigata Chuo Natl Hosp, Dept Neurosurg, Nishi Ku, Niigata 9502085, Japan
来源：
CLINICAL NEUROPHYSIOLOGY | 2015年 / 126卷 / 01期
基金：
日本学术振兴会;
关键词：
Transcranial direct current stimulation; Somatosensory evoked magnetic fields; Primary motor cortex; Primary somatosensory cortex; Magnetoencephalography; Median nerve stimulation; MEDIAN NERVE-STIMULATION; PRIMARY SENSORIMOTOR CORTEX; PARIETAL CORTEX; EXCITABILITY; POTENTIALS; RESPONSES; HUMANS; MODULATION; MEG; MOVEMENT;
D O I：
10.1016/j.clinph.2014.04.014
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Objectives: The purpose of this study was to investigate the effect of anodal transcranial direct-current stimulation (tDCS) applied over the primary motor (M1) or the primary somatosensory (S1) cortices on somatosensory evoked magnetic fields (SEFs) following median nerve stimulation. Methods: Anodal tDCS was applied for 15 min on the left motor or somatosensory cortices at 1 mA. SEFs were recorded following right median nerve stimulation using a magnetoencephalography (MEG) system before and after the application of tDCS. SEFs was measured and compared before and after tDCS was applied over M1 or S1. Results: The source strengths for the P35m and P60m increased after tDCS was applied over M1 and that for the P60m increased after tDCS was applied over S1. The mean equivalent current dipole (ECD) location for the P35m was located significantly anterior to that of the N20m, but only during post 1 (10-20 min after tDCS was applied over M1). Conclusion: Our results indicated that the anodal tDCS applied over M1 affected the P35m and P60m sources on SEF components, while that applied over S1 influenced the P60m source. Significance: We demonstrated anodal tDCS applied over M1 or S1 can modulate somatosensory processing and components of SEFs, confirming the hypothesis for locally distinct generators of the P35m and P60m sources. (C) 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
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收藏
页码：60 / 67
页数：8
相关论文
共 45 条
  • [1] CORTICAL SOMATOSENSORY EVOKED-POTENTIALS .2. EFFECTS OF EXCISION OF SOMATOSENSORY OR MOTOR CORTEX IN HUMANS AND MONKEYS
    ALLISON, T
    WOOD, CC
    MCCARTHY, G
    SPENCER, DD
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 1991, 66 (01) : 64 - 82
  • [2] HUMAN CORTICAL POTENTIALS-EVOKED BY STIMULATION OF THE MEDIAN NERVE .1. CYTOARCHITECTONIC AREAS GENERATING SHORT-LATENCY ACTIVITY
    ALLISON, T
    MCCARTHY, G
    WOOD, CC
    DARCEY, TM
    SPENCER, DD
    WILLIAMSON, PD
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 1989, 62 (03) : 694 - 710
  • [3] TOPOGRAPHY AND INTRA-CRANICAL SOURCES OF SOMATOSENSORY EVOKED-POTENTIALS IN THE MONKEY .2. CORTICAL COMPONENTS
    AREZZO, JC
    VAUGHAN, HG
    LEGATT, AD
    [J]. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1981, 51 (01): : 1 - 18
  • [4] COOPER R, 1975, J PHYSIOL-LONDON, V245, pP70
  • [5] Transcranial direct current stimulation applied over the somatosensory cortex -: Differential effect on low and high frequency SEPs
    Dieckhoefer, Anne
    Waberski, Till Dino
    Nitsche, Michael
    Paulus, Walter
    Buchner, Helmut
    Gobbele, Rene
    [J]. CLINICAL NEUROPHYSIOLOGY, 2006, 117 (10) : 2221 - 2227
  • [6] FORSS N, 1994, EXP BRAIN RES, V99, P309
  • [7] Cortical representation of pain in primary sensory-motor areas (S1/M1)-a study using intracortical recordings in humans
    Frot, Maud
    Magnin, Michel
    Mauguiere, Francois
    Garcia-Larrea, Luis
    [J]. HUMAN BRAIN MAPPING, 2013, 34 (10) : 2655 - 2668
  • [8] MODIFICATION OF MEDIAN NERVE SOMATIC EVOKED-POTENTIALS BY PRIOR MEDIAN NERVE, PERONEAL NERVE, AND AUDITORY-STIMULATION
    GREENWOOD, PM
    GOFF, WR
    [J]. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1987, 68 (04): : 295 - 302
  • [9] Huang MX, 2000, HUM BRAIN MAPP, V11, P59, DOI 10.1002/1097-0193(200010)11:2<59::AID-HBM10>3.0.CO
  • [10] 2-5
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