Polymeric micelles for hydrogen sulfide delivery

被引：24
|
作者：
Hasegawa, Urara [1 ,2 ]
van der Vlies, Andre J. [2 ,3 ]
机构：
[1] Osaka Univ, Grad Sch Engn, Frontier Res Base Young Researchers, Suita, Osaka, Japan
[2] Osaka Univ, Grad Sch Engn, Dept Appl Chem, Suita, Osaka, Japan
[3] Osaka Univ, Grad Sch Engn, Frontier Res Ctr, Suita, Osaka, Japan
来源：
MEDCHEMCOMM | 2015年 / 6卷 / 02期
基金：
日本学术振兴会;
关键词：
INFLAMMATION; CELLS;
D O I：
10.1039/c4md00373j
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Polymeric micelles for therapeutic delivery of hydrogen sulfide (H2S) were developed. The micelles released H2S in murine macrophages and enhanced proinflammatory responses induced by a toll- like receptor 7 ligand, gardiquimod. This micellar H2S delivery system may have potential in immunotherapy and vaccine development.
引用
收藏
页码：273 / 276
页数：4
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