A case of biliary adenofibroma with malignant transformation

被引：21

作者：

Thai, Elena ^{[1
]}

Dalla Valle, Raffaele ^{[2
]}

Evaristi, Francesco ^{[1
]}

Silini, Enrico Maria ^{[1
]}

机构：

[1] Univ Hosp Parma, Surg Pathol Unit, Parma, Italy

[2] Univ Hosp Parma, Gen & Transplantat Surg, Parma, Italy

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2016年 / 212卷 / 05期

关键词：

Biliary adenofibroma; Cholangiocarcinoma; Carcinogenesis; Precursors; BILE-DUCT; CHOLANGIOCARCINOMA; NEOPLASM; ADENOMA; TUMOR;

D O I：

10.1016/j.prp.2015.12.015

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Identifying precursor lesions of cholangiocarcinoma (CC) is relevant for early diagnosis and management. While for distal, perihilar and large duct cholangiocarcinoma, premalignant lesions are being recognized and studied actively, precursors of peripheral CC are still poorly described. Biliary adenofibroma is a rare benign tumor that has been proposed as a possible precursor lesion of peripheral CC. In the present report, we describe a unique case of a peripheral ICC that originated from a benign biliary adenofibroma with areas of atypical papillary proliferation, which is an expression of a multistep process of carcinogenesis. (C) 2016 Elsevier GmbH. All rights reserved.

引用

页码：468 / 470

页数：3

共 19 条

[1] Biliary adenofibroma with malignant transformation and pulmonary metastases: CT findings [J].