Raman dye-labeled nanoparticle probes for proteins

被引：339
作者：
Cao, YC
Jin, RC
Nam, JM
Thaxton, CS
Mirkin, CA
机构：
[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA
[2] Northwestern Univ, Inst Nanotechnol, Evanston, IL 60208 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 48期
关键词：
D O I：
10.1021/ja0366235
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this paper, we demonstrate how one can chemically design Raman dye-functionalized nanoparticle probes with specific protein-binding affinities and use these probes, coupled with surface-enhanced Raman scattering (SERS) spectroscopy, to perform multiplexed screening of protein?small molecule interactions and protein?protein interactions in a protein microarray format. Copyright © 2003 American Chemical Society.
引用
收藏
页码：14676 / 14677
页数：2
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