TRPV4 links inflammatory signaling and neuroglial swelling

被引：26

作者：

Ryskamp, Daniel A. ^{[1
,2
]}

Iuso, Anthony ^{[1
,2
]}

Krizaj, David ^{[1
,2
,3
,4
]}

机构：

[1] Moran Eye Inst, Dept Ophthalmol & Visual Sci, Salt Lake City, UT 84132 USA

[2] Univ Utah, Sch Med, Interdept Program Neurosci, Salt Lake City, UT USA

[3] Univ Utah, Sch Med, Dept Neurobiol & Anat, Salt Lake City, UT USA

[4] Univ Utah, Sch Med, Ctr Translat Med, Salt Lake City, UT USA

来源：

CHANNELS | 2015年 / 9卷 / 02期

关键词：

arachidonic acid; cytotoxic edema; epoxyeicosatrienoic acids; inflammation; neurodegeneration; phospholipase A2; TRPV4; ARACHIDONIC-ACID;

D O I：

10.1080/19336950.2015.1017998

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：70 / 72

页数：3

共 8 条

[1] ARACHIDONIC-ACID AS A MESSENGER IN THE CENTRAL-NERVOUS-SYSTEM [J].

ATTWELL, D ;

MILLER, B ;

SARANTIS, M .

SEMINARS IN THE NEUROSCIENCES, 1993, 5 (03) :159-169

[2] Functions of Astrocytes and their Potential As Therapeutic Targets [J].

Kimelberg, Harold K. ;

Nedergaard, Maiken .

NEUROTHERAPEUTICS, 2010, 7 (04) :338-353

[3] From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma [J].

Krizaj, David ;

Ryskamp, Daniel A. ;

Tian, Ning ;

Tezel, Guelguen ;

Mitchell, Claire H. ;

Slepak, Vladlen Z. ;

Shestopalov, Valery I. .

CURRENT EYE RESEARCH, 2014, 39 (02) :105-119

[4] Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia [J].

Lambert, IH ;

Pedersen, SF ;

Poulsen, KA .

ACTA PHYSIOLOGICA, 2006, 187 (1-2) :75-85

[5] Arachidonic acid and ion channels: an update [J].

Meves, H. .

BRITISH JOURNAL OF PHARMACOLOGY, 2008, 155 (01) :4-16

[6]

Reichenbach A., 2010, Muller cells in the healthy and diseased retina

[7] Swelling and Eicosanoid Metabolites Differentially Gate TRPV4 Channels in Retinal Neurons and Glia [J].

Ryskamp, Daniel A. ;

Jo, Andrew O. ;

Frye, Amber M. ;

Vazquez-Chona, Felix ;

MacAulay, Nanna ;

Thoreson, Wallace B. ;

Krizaj, David .

JOURNAL OF NEUROSCIENCE, 2014, 34 (47) :15689-15700

[8] SWELLING, ACIDOSIS, AND IRREVERSIBLE DAMAGE OF GLIAL-CELLS FROM EXPOSURE TO ARACHIDONIC-ACID IN-VITRO [J].

STAUB, F ;

WINKLER, A ;

PETERS, J ;

KEMPSKI, O ;

KACHEL, V ;

BAETHMANN, A .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1994, 14 (06) :1030-1039

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