Synthesis of phthalides via Pd/CNTs-catalyzed reaction of terminal alkynes and o-iodobenzoic acid under copper- and ligand-free conditions

被引：52

作者：

Zhou, Lei ^{[1
]}

Jiang, Huan-Feng ^{[1
]}

机构：

[1] S China Univ Technol, Coll Chem, Guangzhou 510640, Peoples R China

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 48期

基金：

中国国家自然科学基金;

关键词：

phthalide; palladium; terminal alkynes; copper-free; ligand-free;

D O I：

10.1016/j.tetlet.2007.09.170

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A phosphine- and copper-free protocol for the synthesis of phthalides via Pd/CNTs-catalyzed tandem coupling-cyclization process has been developed. The palladium immobilized on CNTs showed high catalytic activity, and the reactions with a variety of terminal alkynes and o-iodobenoic acid proceeded smoothly to give phthalides in moderate to good yields catalyzed by 0.1% mmol Pd/CNTs. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：8449 / 8452

页数：4

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