What drives depression in empty nose syndrome? A Sinonasal Outcome Test-25 subdomain analysis

被引：15

作者：

Huang, Chien-Chia ^{[1
,2
,3
]}

Wu, Pei-Wen ^{[1
,2
,4
,5
]}

Fu, Chia-Hsiang ^{[1
,2
,3
]}

Huang, Chi-Che ^{[1
,2
,3
]}

Chang, Po-Hung ^{[1
,2
,3
]}

Wu, Ching-Lung ^{[1
,2
]}

Lee, Ta-Jen ^{[1
,2
,6
]}

机构：

[1] Chang Gung Mem Hosp, Dept Otolaryngol, Div Rhinol, 5 Fu Shin St, Taoyuan 333, Taiwan

[2] Chang Gung Univ, 5 Fu Shin St, Taoyuan 333, Taiwan

[3] Chang Gung Univ, Coll Med, Grad Inst Clin Med Sci, Taoyuan, Taiwan

[4] Chang Gung Mem Hosp, Dept Otolaryngologya Head & Neck Surg, Keelung, Taiwan

[5] Chang Gung Univ, Keelung, Taiwan

[6] Xiamen Chang Gung Hosp, Dept Otolaryngol, Xiamen, Fujian, Peoples R China

来源：

RHINOLOGY | 2019年 / 57卷 / 06期

关键词：

beck anxiety inventory; beck depression inventory II; depression; empty nose syndrome; Sinonasal Outcome Test-25; IMPLANTATION; INVENTORY; ANXIETY;

D O I：

10.4193/Rhin19.085

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background: Empty nose syndrome (ENS) is a debilitating disorder characterised by paradoxical nasal obstruction after excessive surgical excision of nasal tissues. ENS negatively impacts the quality of life (QOL) and psychological status of patients. This study aimed to determine the associations among disease-specific QOL impairments and the severity of anxiety and depression before and after surgery in ENS patients. Methods: A total of 68 ENS patients were prospectively recruited and underwent submucosal Medpor implantation. QOL impairments and the severity of anxiety and depression were evaluated using the Sinonasal Outcome Test-25 (SNOT-25), Beck Depression Inventory-II (BDI-II), and Beck Anxiety Inventory (BAI) 1 day before and 6 months after surgery. Results: The BDI-II and BAI scores were significantly associated with the total score and ear/facial symptoms, psychological dysfunction, sleep dysfunction, and empty nose symptoms domains of the SNOT-25. Surgery improved disease-specific and psychological symptoms. Post-operative changes in the BDI-II score were correlated with changes in the total score and sleep dysfunction and empty nose symptoms domains of the SNOT-25. A SNOT-25 total score of > 60, sleep dysfunction domain score of > 18, and empty nose symptoms domain score of > 14 were good predictors of moderate-to-severe depression. Conclusions: ENS symptoms are associated with psychological burden and could be good predictors of moderate-to-severe depression. Targeted symptom improvement could reduce the psychological burden.

引用

页码：469 / 476

页数：8