Hydrolytic microneedles as transdermal drug delivery system

被引：0
|
作者：
Miyano, T. [1 ]
Miyachi, T. [1 ]
Okanishi, T. [1 ]
Todo, H. [2 ]
Sugibayashi, K. [2 ]
Uernura, T. [1 ]
Takano, N. [1 ]
Konishi, S. [1 ]
机构：
[1] Ritsumeikan Univ, Dept Micro Syst Technol, Kusastu, Japan
[2] Josai Univ, Dept Pharmacokinet & Biopharmaceut, Sakado, Saitama, Japan
来源：
TRANSDUCERS '07 & EUROSENSORS XXI, DIGEST OF TECHNICAL PAPERS, VOLS 1 AND 2 | 2007年
关键词：
drug delivery system; microneedle; bio-degradable; hydrolytic;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We developed hydrolytic microneedles as a transdermal drug delivery system to overcome the shortcomings of existing microneedle-systems: long-term stay of broken needles in the skin and high cost for safe disposal of used needles. The present microneedles spontaneously dissolve by hydrolysis in human skin as well as in the (boiled) water. We verified their basic utility through experiments.
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页数：2
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