The effects of transdermal nicotine for the treatment of Hispanic smokers

Objective: To assess the efficacy ol transdermal nicotine as an adjunct to smoking cessation in Hispanics. Design: Randomized, double-blind, placebo-controlled pilot clinical trial. Intervention: Nicotine or placebo transdermal system (patch) and brief individual motivational support. Results: Six-week abstinence rates in the nicotine versus placebo groups were 63 versus 35%, respectively, and were 46 versus 26%, respectively, at PO weeks. These differences in abstinence rates between the two groups were significant at 6 weeks (x(2) = 7.26, p < 0.01) and 10 weeks (x(2) = 4.01, p = 0.05), Withdrawal symptoms were mot suppressed, though weight was suppressed, in the transdermal nicotine group.