Far-infrared in vivo signature of human skin by terahertz time-domain spectroscopy using waveform rebuilding technology

被引:0
|
作者
Li, Xiangjun [1 ]
Liu, Jianjun [1 ]
Hong, Zhi [1 ]
机构
[1] China Jiliang Univ, Ctr THz Res, Hangzhou 310018, Peoples R China
关键词
THz time-domain spectroscopy; waveform rebuilding; human skin; in vivo; CANCER;
D O I
10.1117/12.868453
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present terahertz time-domain spectroscopy characterization of human thumb skin in reflection measurement mode with waveform rebuilding technology. The thumb skin contacts one side of a high resistive silicon wafer with 3 mm thick, and here is an orthogonal incidence of the THz pulse putting on the other side of the wafer. We rebuild the time domain signal from silicon-skin interface as a sample signal by the signal from the air-silicon interface as a reference and a Fresnel transform function between them. Material parameters were calculated by minimizing the difference between the measured sample waveform and a rebuilt one in time domain. The double Debye model parameters for the thumb skin were fitted. The method has potential to research complex layer-structures in skin if a precise model is built.
引用
收藏
页数:6
相关论文
共 50 条
  • [11] A direct comparison between terahertz time-domain spectroscopy and far-infrared Fourier transform spectroscopy
    Han, PY
    Tani, M
    Usami, M
    Kono, S
    Kersting, R
    Zhang, XC
    JOURNAL OF APPLIED PHYSICS, 2001, 89 (04) : 2357 - 2359
  • [12] Far-infrared optical and dielectric response of ZnS measured by terahertz time-domain spectroscopy
    Thamizhmani, L
    Azad, AK
    Dai, JM
    Zhang, W
    APPLIED PHYSICS LETTERS, 2005, 86 (13) : 1 - 3
  • [13] Far-infrared phonon-polariton dispersion probed by terahertz time-domain spectroscopy
    Kojima, S
    Tsumura, N
    Takeda, MW
    Nishizawa, S
    PHYSICAL REVIEW B, 2003, 67 (03)
  • [14] Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy
    Fischer, BM
    Walther, M
    Jepsen, PU
    PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (21): : 3807 - 3814
  • [15] Far-infrared spectroscopic characterization of explosives for security applications using broadband terahertz time-domain spectroscopy
    Fan, W. H.
    Burnett, A.
    Upadhya, P. C.
    Cunningham, J.
    Linfield, E. H.
    Davies, A. G.
    APPLIED SPECTROSCOPY, 2007, 61 (06) : 638 - 643
  • [16] Far-infrared dielectric constant of porous silicon layers measured by terahertz time-domain spectroscopy
    Universite de Savoie, Le Bourget du Lac, France
    J Appl Phys, 11 pt 1 (6007-6010):
  • [17] Far-infrared dielectric constant of porous silicon layers measured by terahertz time-domain spectroscopy
    Labbe-Lavigne, S
    Barret, S
    Garet, F
    Duvillaret, L
    Coutaz, JL
    JOURNAL OF APPLIED PHYSICS, 1998, 83 (11) : 6007 - 6010
  • [18] Orientation Dependent Far-Infrared Terahertz Absorptions in Single Crystal Pentaerythritol Tetranitrate (PETN) Using Terahertz Time-Domain Spectroscopy
    Whitley, Von H.
    Hooks, Daniel E.
    Ramos, Kyle J.
    Pierce, Timothy H.
    O'Hara, John F.
    Azad, Abul K.
    Taylor, Antoinette J.
    Barber, Jeffrey
    JOURNAL OF PHYSICAL CHEMISTRY A, 2011, 115 (04): : 439 - 442
  • [19] Temperature-dependent far-infrared spectra of explosives and drugs measured by terahertz time-domain spectroscopy
    Fan, W. H.
    Burnett, A.
    Upadhya, P. C.
    Cunningham, J.
    Linfield, E. H.
    Davies, A. G.
    CONFERENCE DIGEST OF THE 2006 JOINT 31ST INTERNATIONAL CONFERENCE ON INFRARED AND MILLIMETER WAVES AND 14TH INTERNATIONAL CONFERENCE ON TERAHERTZ ELECTRONICS, 2006, : 232 - 232
  • [20] Terahertz time-domain spectroscopy response of amines and amino acids intercalated smectites in far-infrared region
    Janek, M.
    Zich, D.
    Naftaly, M.
    MATERIALS CHEMISTRY AND PHYSICS, 2014, 145 (03) : 278 - 287