THz time-domain spectroscopy;
waveform rebuilding;
human skin;
in vivo;
CANCER;
D O I:
10.1117/12.868453
中图分类号:
O43 [光学];
学科分类号:
070207 ;
0803 ;
摘要:
We present terahertz time-domain spectroscopy characterization of human thumb skin in reflection measurement mode with waveform rebuilding technology. The thumb skin contacts one side of a high resistive silicon wafer with 3 mm thick, and here is an orthogonal incidence of the THz pulse putting on the other side of the wafer. We rebuild the time domain signal from silicon-skin interface as a sample signal by the signal from the air-silicon interface as a reference and a Fresnel transform function between them. Material parameters were calculated by minimizing the difference between the measured sample waveform and a rebuilt one in time domain. The double Debye model parameters for the thumb skin were fitted. The method has potential to research complex layer-structures in skin if a precise model is built.
机构:
Physics Department, Rensselaer Polytechnic Institute, Troy, NY 12180, United StatesPhysics Department, Rensselaer Polytechnic Institute, Troy, NY 12180, United States
Han, Pengyu
Zhang, Xi-Cheng
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机构:
Physics Department, Rensselaer Polytechnic Institute, Troy, NY 12180, United StatesPhysics Department, Rensselaer Polytechnic Institute, Troy, NY 12180, United States