Dyslipidaemia and atherogenic risk in patients with systemic lupus erythematosus

Introduction: Dyslipidaemia is a common comorbidity in patients with systemic lupus erythematosus. Patients and methods: Fifty-one patients were included. Variables associated with the disease and the drugs used were recorded. Atherogenic risk was calculated. Chi square was used for categorical variables. ANOVA was performed and a logistic regression model to determine the association of the variables with the presence of dyslipidaemia. Results: A percentage of 68.6 had dyslipidaemia. A significant difference between the presence of dyslipidaemia and activity index measured by SLEDAI was found, the presence of lupus nephritis, use of prednisone >= 20 mg/day, evolution of the disease <3 years. Significance between the absence of dyslipidaemia and use of hydroxychloroquine was found. SLEDAI >= 4 and the use of prednisone >= 20 mg/day were independently associated with the presence of dyslipidaemia. The average of Castelli rate was 5.02, the Kannel index was 2.97 and triglyceride/HDL-C ratio was 5.24. Conclusions: Patients with systemic lupus erythematosus have a high prevalence of dyslipidaemia and a high atherogenic rate, which increases cardiovascular risk significantly. (C) 2016 Elsevier Espana, S.L.U. All rights reserved.