Impact of fetal alcohol exposure on body systems: A systematic review

被引:111
作者
Caputo, Courtney [1 ]
Wood, Erin [1 ]
Jabbour, Leila [1 ]
机构
[1] Franklin Pierce Univ, Dept Biol, Div Nat Sci, 40 Univ Dr, Rindge, NH 03461 USA
基金
美国国家卫生研究院;
关键词
fetal alcohol spectrum disorders; fetal alcohol syndrome; prenatal alcohol exposure; alcohol-related birth defects; SPECTRUM DISORDERS; BRAIN; CHILDREN; BEHAVIOR; ETHANOL; INDIVIDUALS; ADOLESCENTS; MORPHOLOGY; LETHALITY; RISK;
D O I
10.1002/bdrc.21129
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Review of published manuscripts on fetal alcohol exposure on several body systems. MethodArticles in this review were found online using databases such as Medline, Medline Complete, PubMed, and Health Source: Nursing/Academic Edition. The following terms were searched: fetal alcohol spectrum disorders, fetal alcohol syndrome, prenatal alcohol exposure, and alcohol related birth defects. ResultsThirteen articles were gathered, five original investigations and eight reviews. This review identified several abnormalities in the body systems discussed and their associations to fetal alcohol syndrome. ConclusionsEvidence shows that the brain was the most severely impacted organ of the body systems discussed. However, prenatal alcohol exposure causes several abnormalities within the heart, kidney, liver, gastrointestinal tract, and the endocrine systems. In addition, preventative measures need to be taken by mothers during pregnancy. Birth Defects Research (Part C), 2016. (c) 2016 Wiley Periodicals, Inc. Birth Defects Research (Part C) 108:174-180, 2016. (c) 2016 Wiley Periodicals, Inc.
引用
收藏
页码:174 / 180
页数:7
相关论文
共 61 条
  • [1] [Anonymous], FETAL LEARNING PSYCH
  • [2] Brain dysmorphology in individuals with severe prenatal alcohol exposure
    Archibald, SL
    Fennema-Notestine, C
    Gamst, A
    Riley, EP
    Mattson, SN
    Jernigan, TL
    [J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2001, 43 (03) : 148 - 154
  • [3] Effects of Prenatal Ethanol Exposure on Postnatal Growth and the Insulin-Like Growth Factor Axis
    Aros, Sofia
    Mills, James L.
    Iniguez, German
    Avila, Alejandra
    Conley, Mary R.
    Troendle, James
    Cox, Christopher
    Cassorla, Fernando
    [J]. HORMONE RESEARCH IN PAEDIATRICS, 2011, 75 (03): : 166 - 173
  • [4] Bar T, 1980, ADV ANAT EMBRYOL CEL, V59, P1, DOI DOI 10.1007/978-3-642-67432-7_1
  • [5] Cingulate gyrus morphology in children and adolescents with fetal alcohol spectrum disorders
    Bjorkquist, Olivia A.
    Fryer, Susanna L.
    Reiss, Allan L.
    Mattson, Sarah N.
    Riley, Edward P.
    [J]. PSYCHIATRY RESEARCH-NEUROIMAGING, 2010, 181 (02) : 101 - 107
  • [6] Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    Carmeliet, P
    Ferreira, V
    Breier, G
    Pollefeyt, S
    Kieckens, L
    Gertsenstein, M
    Fahrig, M
    Vandenhoeck, A
    Harpal, K
    Eberhardt, C
    Declercq, C
    Pawling, J
    Moons, L
    Collen, D
    Risau, W
    Nagy, A
    [J]. NATURE, 1996, 380 (6573) : 435 - 439
  • [7] BRAIN MALFORMATIONS RELATED TO PRENATAL EXPOSURE TO ETHANOL
    CLARREN, SK
    ALVORD, EC
    SUMI, SM
    STREISSGUTH, AP
    SMITH, DW
    [J]. JOURNAL OF PEDIATRICS, 1978, 92 (01) : 64 - 67
  • [8] Functional Neuroimaging in the Examination of Effects of Prenatal Alcohol Exposure
    Coles, Claire D.
    Li, Zhihao
    [J]. NEUROPSYCHOLOGY REVIEW, 2011, 21 (02) : 119 - 132
  • [9] Magnetic resonance and spectroscopic imaging in prenatal alcohol-exposed children: Preliminary findings in the caudate nucleus
    Cortese, Bernadette M.
    Moore, Gregory J.
    Bailey, Beth A.
    Jacobson, Sandra W.
    Delaney-Black, Virginia
    Hannigan, John H.
    [J]. NEUROTOXICOLOGY AND TERATOLOGY, 2006, 28 (05) : 597 - 606
  • [10] MIDLINE CEREBRAL DYSGENESIS, DYSFUNCTION OF THE HYPOTHALAMIC-PITUITARY AXIS, AND FETAL ALCOHOL EFFECTS
    COULTER, CL
    LEECH, RW
    SCHAEFER, GB
    SCHEITHAUER, BW
    BRUMBACK, RA
    [J]. ARCHIVES OF NEUROLOGY, 1993, 50 (07) : 771 - 775