The Americleft Study: An Inter-Center Study of Treatment Outcomes for Patients With Unilateral Cleft Lip and Palate Part 1. Principles and Study Design

被引：83

作者：

Long, Ross E., Jr. ^{[1
,2
]}

Hathaway, Ronald ^{[1
,3
]}

Daskalogiannakis, John ^{[1
,4
,5
]}

Mercado, Ana ^{[1
,6
]}

Russell, Kathleen ^{[1
,7
,8
]}

Cohen, Marilyn ^{[1
,9
]}

Semb, Gunvor ^{[1
,10
,11
,12
]}

Shaw, William ^{[1
,12
]}

机构：

[1] Dalhousie Univ, Fac Dent, Div Orthodont, Halifax, NS B3H 3J5, Canada

[2] Penn State Coll Med, Dept Surg, Lancaster Cleft Palate Clin, Lancaster, PA USA

[3] Peyton Manning Childrens Hosp St Vincent, Craniofacial Ctr, Indianapolis, IN USA

[4] Univ Toronto, SickKids Hosp, Toronto, ON, Canada

[5] Univ Toronto, Dept Orthodont, Toronto, ON, Canada

[6] Ohio State Univ, Coll Dent, Div Orthodont, Columbus, OH 43210 USA

[7] Dalhousie Univ, Div Orthodont, Halifax, NS, Canada

[8] IWK Hlth Ctr, Cleft Palate Team, Halifax, NS, Canada

[9] Cooper Univ Hosp, Reg Cleft Craniofacial Program, Moorestown, NJ USA

[10] Univ Oslo, Fac Dent, Oslo, Norway

[11] Oslo Cleft Team, Dept Plast Surg, Oslo, Norway

[12] Univ Manchester, Manchester, Lancs, England

来源：

CLEFT PALATE CRANIOFACIAL JOURNAL | 2011年 / 48卷 / 03期

关键词：

Americleft; cleft lip and palate; intercenter study; treatment outcome measures;

D O I：

10.1597/09-180.1

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Objective: The Americleft study is a North American initiative to undertake an intercenter outcome study for patients with repaired complete unilateral cleft lip and palate from five well-established North American cleft centers. Design: Retrospective cohort study. Setting: Five cleft palate centers in North America. Methods: This is the first paper in a series of five that outlines the overall goals of the study and sets the basis for the clinical outcome studies that are reported in the following four papers. The five centers' samples and treatment protocols as well as the methods used for each study are reported. The challenges encountered and possible mechanisms to resolve them and reduce methodological error with intercenter studies are also reviewed.

引用

页码：239 / 243

页数：5

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