Treatment of esophagogastric junction carcinoma: An unsolved debate

被引:7
|
作者
Orditura, Michele [1 ]
Galizia, Gennaro [2 ]
Lieto, Eva [2 ]
De Vita, Ferdinando [1 ]
Ciardiello, Fortunato [1 ]
机构
[1] Univ Naples 2, Dept Internal & Expt Med Magrassi, Sch Med, Div Med Oncol, I-80131 Naples, Italy
[2] Univ Naples 2, Sch Med, Dept Anesthesiol Surg & Emergency Sci, Div Surg, I-80131 Naples, Italy
关键词
Barrett's esophagus; Esophagogastric junction adenocarcinoma; Endoscopic resection; Surgery; Chemotherapy; Chemoradiotherapy; LIMITED TRANSHIATAL RESECTION; ESOPHAGEAL CANCER; GASTROESOPHAGEAL ADENOCARCINOMA; PREOPERATIVE CHEMORADIOTHERAPY; PERIOPERATIVE CHEMOTHERAPY; NEOADJUVANT CHEMOTHERAPY; RADIOFREQUENCY ABLATION; ENDOSCOPIC RESECTION; BARRETTS DYSPLASIA; GRADE DYSPLASIA;
D O I
10.3748/wjg.v21.i15.4427
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The incidence of esophagogastric junction adenocarcinoma (AEG) is increasing worldwide. Barrett's esophagus (BE) associated with dysplasia is the main risk factor for the development of cancer. Currently, screening programs to individuate and eradicate BE represent the best way to reduce AEG cancer. Several endoscopic approaches are here discussed. Surgical strategies for different types of AEG cancer are now fairly standardized, and multidisciplinary strategies using chemotherapy or chemoradiotherapy may improve the outcome of these patients. Here we briefly discuss the keypoints, main topics, and critical issues, according to accumulating evidence and taking into account our own experience.
引用
收藏
页码:4427 / 4431
页数:5
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