Interferon-α for IgM nephropathy?

被引：1

作者：

Liu, Sha ^{[1
]}

Zhang, Dongliang ^{[1
]}

Zhang, Qidong ^{[1
]}

Liu, Wenhu ^{[1
]}

机构：

[1] Capital Med Univ, Beijing Friendship Hosp, Fac Nephrol, Dept Nephrol, Beijing 100050, Peoples R China

来源：

CLINICAL NEPHROLOGY | 2014年 / 82卷 / 02期

关键词：

immunoglobulin M nephropathy; interferon-alpha; nephrotic syndrome; glomerulonephritis; FOCAL SEGMENTAL GLOMERULOSCLEROSIS; MESANGIAL PROLIFERATIVE GLOMERULONEPHRITIS; NECROSIS-FACTOR-ALPHA; CHRONIC HEPATITIS-C; IFN-ALPHA; RECEPTOR ANTAGONIST; VIRUS-INFECTION; THERAPY; GAMMA; INTERLEUKIN-6;

D O I：

10.5414/CN107793

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Immunoglobulin M (IgM) nephropathy is an idiopathic glomerulonephritis characterized by mesangial deposits of IgM. IgM nephropathy presenting with proteinuria, especially nephrotic syndrome, frequently is steroid-dependent or steroid-resistant and associated with reaching end-stage renal disease after a 15-year follow-up. Because no long-term effective treatment is known for patients with IgM nephropathy, there is a clear need for therapeutic alternatives. We describe a patient with IgM nephropathy represented by recurrence of nephrotic syndrome who achieved long-term remission with interferon-alpha sustained treatment.

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收藏

页码：133 / 137

页数：5

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