Immunotherapy with ipilimumab plus nivolumab in a stage IV melanoma patient during pregnancy

被引:40
作者
Menzer, Christian [1 ,2 ]
Beedgen, Bernd [3 ]
Rom, Joachim [4 ]
Duffert, Christin M. [5 ]
Volckmar, Anna-Lena [6 ]
Sedlaczek, Oliver [7 ,8 ]
Richtig, Erika [9 ]
Enk, Alexander [10 ]
Jaeger, Dirk [11 ,12 ,13 ]
Hassel, Jessica C. [1 ]
机构
[1] Heidelberg Univ, Sect DermatoOncol, Dept Dermatol, Natl Ctr Tumor Dis NCT, Heidelberg, Germany
[2] Mem Sloan Kettering Canc Ctr, Dermatol Serv, 1275 York Ave, New York, NY 10021 USA
[3] Heidelberg Univ, Div Neonatol, Dept Pediat, Sch Med, Neuenheimer Feld 430, D-69120 Heidelberg, Germany
[4] Univ Hosp, Dept Obstet & Gynecol, Heidelberg, Germany
[5] Heidelberg Univ, Dept Pediat, Heidelberg, Germany
[6] Univ Hosp Heidelberg, Inst Pathol, Heidelberg, Germany
[7] Univ Hosp Heidelberg, Natl Ctr Tumor Dis NCT, Heidelberg, Germany
[8] Univ Hosp Heidelberg, Dept Diagnost Radiol, German Canc Res Ctr DKFZ, Heidelberg, Germany
[9] Med Univ Graz, Dept Dermatol, Graz, Austria
[10] Heidelberg Univ, Dept Dermatol, Heidelberg, Germany
[11] Univ Hosp Heidelberg, Natl Ctr Tumor Dis NCT, Dept Med Oncol & Internal Med 6, Heidelberg, Germany
[12] German Canc Consortium DKTK, Heidelberg, Germany
[13] German Canc Res Ctr, Appl Tumor Immun, Heidelberg, Germany
关键词
MALIGNANT-MELANOMA; ANTIBODIES; BLOCKADE;
D O I
10.1016/j.ejca.2018.09.008
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:239 / 242
页数:4
相关论文
共 12 条
[1]   Metastatic melanoma in pregnancy: Risk of transplacental metastases in the infant [J].
Alexander, A ;
Samlowski, WE ;
Grossman, D ;
Bruggers, CS ;
Harris, RM ;
Zone, JJ ;
Noyes, RD ;
Bowen, GM ;
Leachman, SA .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (11) :2179-2186
[2]   Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis [J].
Bertrand, Anne ;
Kostine, Marie ;
Barnetche, Thomas ;
Truchetet, Marie-Elise ;
Schaeverbeke, Thierry .
BMC MEDICINE, 2015, 13
[3]   Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets [J].
Bugelski, Peter J. ;
Martin, Pauline L. .
BRITISH JOURNAL OF PHARMACOLOGY, 2012, 166 (03) :823-846
[4]   Hormones, nevi, and melanoma: An approach to the patient [J].
Driscoll, Marcia S. ;
Grant-Kels, Jane M. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2007, 57 (06) :919-931
[5]   New systemic agents in dermatology with respect to fertility, pregnancy, and lactation [J].
Grunewald, Sonja ;
Jank, Alexander .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2015, 13 (04) :277-292
[6]   Combined immune checkpoint blockade (anti-PD-1/anti-CTLA-4): Evaluation and management of adverse drug reactions [J].
Hassel, Jessica C. ;
Heinzerling, Lucie ;
Aberle, Jens ;
Baehr, Oliver ;
Eigentler, Thomas K. ;
Grimm, Marc-Oliver ;
Gruenwald, Victor ;
Leipe, Jan ;
Reinmuth, Niels ;
Tietze, Julia K. ;
Trojan, Joerg ;
Zimmer, Lisa ;
Gutzmer, Ralf .
CANCER TREATMENT REVIEWS, 2017, 57 :36-49
[7]  
Holtan SG, 2009, MAYO CLIN PROC, V84, P985, DOI 10.1016/S0025-6196(11)60669-1
[8]   Applicability of reference values for the determination of serum S100 protein as a marker of malignant melanoma in children [J].
Hunzelmann, N ;
Kurschat, P ;
Hani, N ;
Jarisch, A ;
Mauch, C .
BRITISH JOURNAL OF DERMATOLOGY, 2002, 146 (03) :536-537
[9]   Treatment of Metastatic Malignant Melanoma With Vemurafenib During Pregnancy [J].
Maleka, Aglaia ;
Enblad, Gunilla ;
Sjors, Gunnar ;
Lindqvist, Anna ;
Ullenhag, Gustav J. .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (11) :E192-E193
[10]  
Mehta Andrew, 2018, J Glob Oncol, V4, P1, DOI 10.1200/JGO.17.00019