Hepatic steatosis and respiratory diseases: a new panorama

被引:15
作者
Botello-Manilla, Alan Eduardo [1 ]
Lopez-Sanchez, Guillermo Nahum [1 ]
Chavez-Tapia, Norberto Carlos [1 ,2 ]
Uribe, Misael [2 ]
Nuno-Lambarri, Natalia [1 ]
机构
[1] Med Clin & Fdn, Traslat Res Unit, Puente Piedra 150,Toriello Guerra Tlalpan, Mexico City 14050, DF, Mexico
[2] Med Clin & Fdn, Obes & Digest Dis Unit, Puente Piedra 150,Toriello Guerra Tlalpan, Mexico City 14050, DF, Mexico
关键词
Asthma; Chronic obstructive pulmonary disease; Inflammation; Obstructive sleep apnea; Pulmonary cancer; FATTY LIVER-DISEASE; OBSTRUCTIVE SLEEP-APNEA; INSULIN-RESISTANCE; PULMONARY-DISEASE; ADIPOSE-TISSUE; GROWTH-FACTOR; OBESITY; RISK; IDENTIFICATION; EPIDEMIOLOGY;
D O I
10.1016/j.aohep.2021.100320
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Non-alcoholic fatty liver disease is defined as hepatic fat accumulation in more than 5% of hepatocytes, without other liver steatosis causes. It comprises a broad spectrum that can range from benign steatosis and progress to non-alcoholic steatohepatitis, fibrosis, and ultimately hepatocellular carcinoma. Nonalcoholic fatty liver is considered a multisystemic disease since it is related to multiple disorders, such as type 2 diabetes mellitus, polycystic ovary syndrome, chronic kidney disease, psoriasis, osteoporosis, hypothyroidism, cardiovascular diseases, and obstructive sleep apnea syndrome; it is becoming increasingly clear that it is also a risk factor for developing certain respiratory diseases. This article aims to understand the liver and chronic obstructive pulmonary disease mechanisms, obstructive sleep apnea syndrome, asthma, and lung cancer. Given that non-alcoholic fatty liver disease has a considerable impact on the patient's well-being and life quality, as well as on the costs they generate for the country's health services, it is essential to continue research, especially in areas such as the respiratory tract, as there is much misinformation about it. (c) 2021 Fundacion Clinica Medica Sur, A.C. Published by Elsevier Espa?a, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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页数:6
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