The Effect of Hemoglobin Concentration on Hyperbaric Oxygen and Non-hyperbaric Oxygen in the Treatment of Hypertensive Intracerebral Hemorrhage After Operation at the High Altitude

被引：1

作者：

Wei, Linjie ^{[1
]}

Lin, Chi ^{[2
]}

Xue, Xingsen ^{[3
]}

Jila, Shiju ^{[3
]}

Dai, Yalan ^{[3
]}

Pan, Li ^{[4
]}

Wei, Wei ^{[1
]}

Dun, Guodong ^{[1
]}

Shen, Yong ^{[2
]}

Zong, Taoxi ^{[2
]}

Wu, Jingjing ^{[2
]}

Li, Yafang ^{[2
]}

Wu, Lixia ^{[2
]}

Xian, Jishu ^{[3
]}

Yu, Anyong ^{[5
]}

机构：

[1] PLA 956th Hosp, Dept Neurosurg, Linzhi, Peoples R China

[2] First Peoples Hosp Honghe City, Dept Neurosurg, Honghe, Peoples R China

[3] Third Mil Med Univ, Army Med Univ, Southwest Hosp, Dept Neurosurg, Chongqing, Peoples R China

[4] Gen Hosp Tibet Mil Reg, Med Imaging Dept, Lhasa, Peoples R China

[5] Affiliated Hosp Zunyi Med Univ, Dept Emergency, Zunyi, Peoples R China

来源：

FRONTIERS IN HUMAN NEUROSCIENCE | 2022年 / 16卷

基金：

中国国家自然科学基金;

关键词：

high altitude; puncture and drainage hematoma; hyperbaric oxygen; computed tomography perfusion imaging; hemoglobin concentration; CEREBRAL INFARCTION; THERAPY; INJURY;

D O I：

10.3389/fnhum.2022.834427

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

BackgroundThe prognosis of hypertensive intracerebral hemorrhage (HICH) is poor at high altitudes. The objective of this study was to explore whether hyperbaric oxygen (HBO) can improve the results of computed tomography perfusion (CTP) imaging and the neurological function of patients with HICH, and influence the hemoglobin concentration. MethodThe patients with HICH were treated with puncture and drainage. Twenty-one patients (51.22% of 41 patients in total) were treated with HBO after the operation, and the other patients received conventional treatment. CTP was performed twice, and all indices were measured. Scatter plots were used to determine the effect of hemoglobin concentration on CTP imaging. Receiver operating characteristic (ROC) curves were plotted to analyze the effects of hemoglobin concentration and hematoma volume on recovery results. The patients were followed up for 6 months. ResultsForty-one patients with HICH were treated with puncture and drainage. In total, 21 were treated with HBO after the operation, and 20 received conventional treatment as the control group. No significant differences in the CBV and CBF values of the two groups were noted before treatment. After 10 days, the values of CBV and CBF in the HBO group were significantly higher than those in the control group. A scatter diagram showed there was no significant in the HBO group, but significant correlation for the CBV and CBF values in the control group's hematoma center and margin. The ROC curves showed that hematoma volume had an influence on prognosis of the control group. The Glasgow Coma Scale (GOS) scores of the HBO group were significantly higher than those of the control group (p < 0.05). ConclusionsHBO therapy can improve the postoperative CBV and CBF values of patients with HICH and ameliorate their prognoses. There was no significant correlation between HBO group and hemoglobin concentration on admission.

引用

页数：8

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