Ethical Issues in Developing Pharmacogenetic Research Partnerships With American Indigenous Communities

被引：40

作者：

Boyer, B. B. ^{[1
]}

Dillard, D. ^{[2
]}

Woodahl, E. L. ^{[3
]}

Whitener, R. ^{[4
]}

Thummel, K. E. ^{[5
]}

Burke, W. ^{[6
]}

机构：

[1] Univ Alaska Fairbanks, Ctr Alaska Native Hlth Res, Fairbanks, AK USA

[2] Southcent Fdn, Res Dept, Anchorage, AK USA

[3] Univ Montana, Dept Biomed & Pharmaceut Sci, Missoula, MT 59812 USA

[4] Univ Washington, Sch Law, Native Amer Law Ctr, Seattle, WA 98195 USA

[5] Univ Washington, Dept Pharmaceut, Seattle, WA 98195 USA

[6] Univ Washington, Dept Bioeth & Humanities, Seattle, WA 98195 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2011年 / 89卷 / 03期

关键词：

D O I：

10.1038/clpt.2010.303

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Pharmacogenetic research offers the potential to improve the safety and efficacy of drug prescribing. Assuring that the benefits of this research reach indigenous and other medically underserved people is an important justice concern. First, however, a legacy of mistrust, derived from traditional research practices that disempower communities, must be overcome. Linking pharmacogenetic research to collaborative, power-sharing research partnerships provides a valuable opportunity to develop new and positive precedents for genetic research in indigenous communities.

引用

页码：342 / 345

页数：4

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