Application of stereotactic body radiation therapy to cancer liver metastasis

被引:4
作者
Zhang, Si-Yuan [1 ]
Zhu, Guang-Ying [1 ]
Li, Gong [2 ]
Zhang, Yi-Bao [1 ]
Geng, Jian-Hao [1 ]
机构
[1] Peking Univ, Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res, Minist Educ,Dept Radiat Oncol, 52 Fucheng Rd, Beijing 100142, Peoples R China
[2] Gen Hosp Armed Police Forces, Dept Oncol 2, Beijing 100039, Peoples R China
关键词
SBRT; Liver; Metastasis and radiotherapy; PHASE-I; RADIOFREQUENCY ABLATION; RADIOTHERAPY; TUMORS; LUNG; TRIAL; SBRT;
D O I
10.1016/j.cantet.2015.10.029
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
As an accurate external beam irradiation method, stereotactic body radiotherapy (SBRT) has been increasingly used to deliver high dose in less fractions. The liver is one of the most common organs for cancer metastasis. Recently, there have been several trials applying SBRT to cancer liver metastasis and have proved to be effective and safe with local control (LC) rates ranging from 70% to 100% within one or two years and 2-year overall survival (OS) rates ranging from 30% to 38%. Many published studies indicate that SBRT for cancer liver metastasis results in good outcomes without severe toxicities. However, the validated contribution of SBRT to an improved progression-free survival is still missing and more randomized trials should be conducted. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:225 / 229
页数:5
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