Contribution of Malabsorption to Weight Loss After Roux-en-Y Gastric Bypass: a Systematic Review

被引:63
作者
Mahawar, Kamal K. [1 ]
Sharples, Alistair J. [2 ]
机构
[1] Sunderland Royal Hosp, Bariatr Unit, Sunderland SR4 7TP, Tyne & Wear, England
[2] Univ Hosp North Midlands, Dept Upper GI & Bariatr Surg, Stoke On Trent, Staffs, England
关键词
Gastric bypass; Roux-en-Y-gastric bypass; Malabsorption; Malabsorptive; Absorption; Carbohydrate; Protein; Fat; BARIATRIC SURGERY; GLUCOSE-ABSORPTION; GUT ADAPTATION; MECHANISMS; OBESITY; BEHAVIOR; TRANSIT; MEAL;
D O I
10.1007/s11695-017-2762-y
中图分类号
R61 [外科手术学];
学科分类号
摘要
Roux-en-Y gastric bypass (RYGB) is traditionally classified as a combined restrictive and malabsorptive operation. This notion of the operation influences its technical variations and revisions for patients who do not achieve significant weight loss after this surgery. There is an increasing body of literature suggesting a role for appetite suppression mediated by neuro-hormonal signals after RYGB. The purpose of this paper was to systematically review published English language scientific literature to determine the role of malabsorption towards weight loss achieved with RYGB. This review finds that there is little or no malabsorption of carbohydrates or protein after RYGB but there is some fat malabsorption. Overall, malabsorption makes a little (approximately 11.0% in the early period) overall contribution to weight loss after RYGB.
引用
收藏
页码:2194 / 2206
页数:13
相关论文
共 36 条
[1]   Breath Hydrogen as a Biomarker for Glucose Malabsorption after Roux-en-Y Gastric Bypass Surgery [J].
Andalib, Iman ;
Shah, Hiral ;
Bal, Bikram S. ;
Shope, Timothy R. ;
Finelli, Frederick C. ;
Koch, Timothy R. .
DISEASE MARKERS, 2015, 2015 :1-7
[2]   Alterations in Gastrointestinal, Endocrine, and Metabolic Processes After Bariatric Roux-en-Y Gastric Bypass Surgery [J].
Anderwald, Christian-Heinz ;
Tura, Andrea ;
Promintzer-Schifferl, Miriam ;
Prager, Gerhard ;
Stadler, Marietta ;
Ludvik, Bernhard ;
Esterbauer, Harald ;
Bischof, Martin Georg ;
Luger, Anton ;
Pacini, Giovanni ;
Krebs, Michael .
DIABETES CARE, 2012, 35 (12) :2580-2587
[3]   Bariatric Surgery and Endoluminal Procedures: IFSO Worldwide Survey 2014 [J].
Angrisani, L. ;
Santonicola, A. ;
Iovino, P. ;
Vitiello, A. ;
Zundel, N. ;
Buchwald, H. ;
Scopinaro, N. .
OBESITY SURGERY, 2017, 27 (09) :2279-2289
[4]   Accelerated protein digestion and amino acid absorption after Roux-en-Y gastric bypass [J].
Bojsen-Moller, Kirstine N. ;
Jacobsen, Siv H. ;
Dirksen, Carsten ;
Jorgensen, Nils B. ;
Reitelseder, Soren ;
Jensen, Jens-Erik B. ;
Kristiansen, Viggo B. ;
Holst, Jens J. ;
van Hall, Gerrit ;
Madsbad, Sten .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2015, 102 (03) :600-607
[5]   Exocrine Pancreatic Insufficiency after Roux-en-Y gastric bypass [J].
Borbely, Yves ;
Plebani, Andrin ;
Kroll, Dino ;
Ghisla, Simone ;
Nett, Philipp C. .
SURGERY FOR OBESITY AND RELATED DISEASES, 2016, 12 (04) :790-794
[6]   Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety [J].
Borg, CM ;
le Roux, CW ;
Ghatei, MA ;
Bloom, SR ;
Patel, AG ;
Aylwin, SJB .
BRITISH JOURNAL OF SURGERY, 2006, 93 (02) :210-215
[7]  
BRADLEY EL, 1977, SURGERY, V81, P684
[8]   Long-Term Effects of Bariatric Surgery on Meal Disposal and β-Cell Function in Diabetic and Nondiabetic Patients [J].
Camastra, Stefania ;
Muscelli, Elza ;
Gastaldelli, Amalia ;
Holst, Jens J. ;
Astiarraga, Brenno ;
Baldi, Simona ;
Nannipieri, Monica ;
Ciociaro, Demetrio ;
Anselmino, Marco ;
Mari, Andrea ;
Ferrannini, Ele .
DIABETES, 2013, 62 (11) :3709-3717
[9]   The Effect of Bariatric Surgery on Intestinal Absorption and Transit Time [J].
Carswell, Kirstin A. ;
Vincent, Royce P. ;
Belgaumkar, Ajay P. ;
Sherwood, Roy A. ;
Amiel, Stephanie A. ;
Patel, Ameet G. ;
le Roux, Carel W. .
OBESITY SURGERY, 2014, 24 (05) :796-805
[10]   Distal small bowel bypass for weight regain after gastric bypass: safety and efficacy threshold occurs at <70% bypass [J].
Caruana, Joseph A. ;
Monte, Scott V. ;
Jacobs, David M. ;
Voytovich, Catherine ;
Ghanim, Husam ;
Dandona, Paresh .
SURGERY FOR OBESITY AND RELATED DISEASES, 2015, 11 (06) :1248-1255