Ischemic Cardiac Complications Following G-CSF

被引：12

作者：

Eckman, Peter M. ^{[1
]}

Bertog, Stefan C. ^{[2
]}

Wilson, Robert F. ^{[1
]}

Henry, Timothy D. ^{[3
]}

机构：

[1] Univ Minnesota, Dept Med, Div Cardiol, Minneapolis, MN 55455 USA

[2] Minneapolis VA Med Ctr, Dept Med, Div Cardiol, Minneapolis, MN USA

[3] Abbott NW Hosp, Minneapolis Heart Inst Fdn, Minneapolis, MN 55407 USA

来源：

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS | 2010年 / 76卷 / 01期

关键词：

filgrastim/adverse effects; coronary artery disease; myocardial infarction; inflammation; COLONY-STIMULATING FACTOR; ACUTE MYOCARDIAL-INFARCTION; CORONARY-ARTERY-DISEASE; STEM-CELL MOBILIZATION; HEART-DISEASE; PLATELET-AGGREGATION; NORMAL DONORS; SAFETY; EFFICACY; TRIAL;

D O I：

10.1002/ccd.22455

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Granulocyte-colony stimulating factor (G-CSF) is commonly used in bone marrow transplant donors to increase the number of circulating progenitor cells. G-CSF has also been studied following myocardial infarction, but concern has been raised about the risks of G-CSF administration in patients with coronary artery disease. We present two cases of ischemic cardiac complications that are likely to be related to administration of G-CSF and provide a contemporary overview of the literature on the cardiovascular risks of G-CSF. (C) 2010 Wiley-Liss, Inc.

引用

页码：98 / 101

页数：4

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