Evaluation of the autonomic imbalance in the patient with positive serology for Chagas disease Diagnostic and treatment score

被引：0

作者：

Gimenez, Luisa J. ^{[1
]}

Mitelman, Jorge E. ^{[1
]}

Sabra, Ahmad H. ^{[1
]}

Justiniano Encina, Juan ^{[1
]}

Uriona Villarroel, Juan ^{[1
]}

Maldonado, Ninoska ^{[1
]}

Fernandez Chamorro, Felipe Nery Gervacio ^{[1
]}

Luces Leon, Raquel M. ^{[1
]}

Aguirre, Fernando ^{[1
]}

Mendoza, Ivan ^{[1
]}

Macedo Linares, Ana Maria ^{[1
]}

Bonilla, Rafael ^{[1
]}

Blandon Calderon, Roberto ^{[1
]}

Linarez Ochoa, Nery E. ^{[1
]}

Reyes Lopez, Pedro A. ^{[1
]}

Gutierrez Perucho, Ernesto ^{[1
]}

Melnikov, Valery ^{[1
]}

Romero, Analia ^{[1
]}

Gonzalez, Marcos E. ^{[1
]}

机构：

[1] Fac Med Barcelo, Dept Atenc Primaria, Buenos Aires, DF, Argentina

来源：

INSUFICIENCIA CARDIACA | 2021年 / 16卷 / 02期

关键词：

Chagas disease; Heart failure; Chagas cardiomyopathy; Latin America; Trypanosoma cruzi; Autonomic nervous system; Chagas dysautonomia; PATHOGENESIS; DYSFUNCTION; AUTOIMMUNE; ANTIBODIES; TRIAL; IGG;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chagas disease is a parasitic disease (Trypanosoma cruzi), endemic in 21 countries of America and that migrations have dispersed it in different continents. One of the earliest manifestations of this disease is dysautonomic alterations or autonomic dysfunction. The severity of this inadequate functioning of the autonomic nervous system is measurable, so that the evolution and/or progression of the disease can be verified by altering clinical studies and detecting antimuscarinic antibodies. These antibodies are present in 30% of those infected and appear very early once the parasitosis is installed; In addition, other studies, such as QT dispersion (> 65 ms) and heart rate variability (<100 ms) show abnormal values. The use of new paradigms of care, diagnosis and appropriate treatments are essential to prevent the development of this heart disease.

引用

页码：52 / 59

页数：8

共 38 条

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