Does hypertriglyceridemia increase risk for CAD? Growing evidence suggests it plays a role

被引：20

作者：

Coughlan, BJ ^{[1
]}

Sorrentino, MJ ^{[1
]}

机构：

[1] Univ Chicago, Pritzker Sch Med, Dept Med, Sect Cardiol, Chicago, IL 60637 USA

来源：

POSTGRADUATE MEDICINE | 2000年 / 108卷 / 07期

关键词：

D O I：

10.3810/pgm.2000.12.1314

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Although the role of high serum triglyceride levels in coronary artery disease (CAD) has been debated, evidence now points to a link, Triglyceride-lowering treatments, including diet and exercise modifications and pharamacotherapy, can reduce the risk of CAD. Drs Coughlan and Sorrentino review the accumulated study findings, describe primary and acquired hypertriglyceridemia, and discuss the various approaches to treating these conditions.

引用

页码：77 / 84

页数：8

共 21 条

[1] RELATION OF HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL AND TRIGLYCERIDES TO INCIDENCE OF ATHEROSCLEROTIC CORONARY-ARTERY DISEASE (THE PROCAM EXPERIENCE) [J].

ASSMANN, G ;

SCHULTE, H .

AMERICAN JOURNAL OF CARDIOLOGY, 1992, 70 (07) :733-737

[2] GENETIC (PRIMARY) FORMS OF HYPERTRIGLYCERIDEMIA [J].

ASSMANN, G ;

BREWER, HB .

AMERICAN JOURNAL OF CARDIOLOGY, 1991, 68 (03) :A13-A16

[3] ATHEROGENIC LIPOPROTEIN PHENOTYPE - A PROPOSED GENETIC-MARKER FOR CORONARY HEART-DISEASE RISK [J].

AUSTIN, MA ;

KING, MC ;

VRANIZAN, KM ;

KRAUSS, RM .

CIRCULATION, 1990, 82 (02) :495-506

[4] PLASMA TRIGLYCERIDE AND CORONARY HEART-DISEASE [J].

AUSTIN, MA .

ARTERIOSCLEROSIS AND THROMBOSIS, 1991, 11 (01) :2-14

[5] COMBINED EFFECTS OF HDL CHOLESTEROL, TRIGLYCERIDE, AND TOTAL CHOLESTEROL CONCENTRATIONS ON 18-YEAR RISK OF ATHEROSCLEROTIC DISEASE [J].

BURCHFIEL, CM ;

LAWS, A ;

BENFANTE, R ;

GOLDBERG, RJ ;

HWANG, LJ ;

CHIU, D ;

RODRIGUEZ, BL ;

CURB, JD ;

SHARP, DS .

CIRCULATION, 1995, 92 (06) :1430-1436

[6]

CANNY JF, 1986, PAMI, V8, P6, DOI DOI 10.1109/TPAMI.1986.4767851

[7] EPIDEMIOLOGY OF TRIGLYCERIDES - A VIEW FROM FRAMINGHAM [J].

CASTELLI, WP .

AMERICAN JOURNAL OF CARDIOLOGY, 1992, 70 (19) :H3-H9

[8] PLASMA TRIGLYCERIDE LEVEL AND MORTALITY FROM CORONARY HEART-DISEASE [J].

CRIQUI, MH ;

HEISS, G ;

COHN, R ;

COWAN, LD ;

SUCHINDRAN, CM ;

BANGDIWALA, S ;

KRITCHEVSKY, S ;

JACOBS, DR ;

OGRADY, HK ;

DAVIS, CE .

NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (17) :1220-1225

[9] Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels - Results of AFCAPS/TexCAPS [J].

Downs, JR ;

Clearfield, M ;

Weis, S ;

Whitney, E ;

Shapiro, DR ;

Beere, PA ;

Langendorfer, A ;

Stein, EA ;

Kruyer, W ;

Gotto, AM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (20) :1615-1622

[10] HELSINKI HEART-STUDY - PRIMARY-PREVENTION TRIAL WITH GEMFIBROZIL IN MIDDLE-AGED MEN WITH DYSLIPIDEMIA - SAFETY OF TREATMENT, CHANGES IN RISK-FACTORS, AND INCIDENCE OF CORONARY HEART-DISEASE [J].

FRICK, MH ;

ELO, O ;

HAAPA, K ;

HEINONEN, OP ;

HEINSALMI, P ;

HELO, P ;

HUTTUNEN, JK ;

KAITANIEMI, P ;

KOSKINEN, P ;

MANNINEN, V ;

MAENPAA, H ;

MALKONEN, M ;

MANTTARI, M ;

NOROLA, S ;

PASTERNACK, A ;

PIKKARAINEN, J ;

ROMO, M ;

SJOBLOM, T ;

NIKKILA, EA .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (20) :1237-1245

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