Structure elucidation and NMR assignments of new spirosolane alkaloids from Solanum campaniforme

被引：3

作者：

Torres, Maria Conceicao M. ^{[1
]}

Almeida, Jose Gustavo L. ^{[1
]}

Braz-Filho, Raimundo ^{[1
]}

Silveira, Edilberto R. ^{[1
]}

Pessoa, Otilia Deusdenia L. ^{[1
]}

机构：

[1] Univ Fed Ceara, Dept Quim Organ & Inorgan, BR-60021970 Fortaleza, CE, Brazil

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2012年 / 50卷 / 01期

关键词：

H-1; NMR; C-13; Solanum campaniforme; spirosolane steroidal alkaloids; MOLLUSCICIDAL ACTIVITY; GLYCOALKALOIDS; GLYCOSIDES;

D O I：

10.1002/mrc.3793

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

From the leaves of Solanum campaniforme, two new spirosolane alkaloids beta-acetoxyl-(25S)-22 beta N-spirosol-4-en-3-one (1) and beta-hydroxyl-(25S)-22 beta N-spirosol-4-en-3-one (4) were isolated along with two other known alkaloids of the same class (25S)-22 beta N-spirosol-1,4-dien-3-one (2) and (25S)-22 beta N-spirosol-4-en-3-one (3), which are reported for the first time as natural products. The structures of all alkaloids were established after an extensive analysis by 1D and 2D NMR spectroscopy (COSY, HSQC, HMBC and NOESY) as well as HRESIMS. Copyright (c) 2012 John Wiley & Sons, Ltd.

引用

页码：74 / 78

页数：5

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