Fatal colon cancer in a young egg donor: a physician mother's call for follow-up and research on the long-term risks of ovarian stimulation

Objective: To present a case report of fatal colon cancer in a young, previously healthy woman 4 years after repeated ovarian stimulation for egg donation, review previous publications on the risks of ovarian stimulation, and make recommendations for further egg donor follow-up, research, and actions by professional associations and regulatory agencies. Design: Case report and review of the literature. Setting: Case report and review of the literature. Patient(s): One patient and published cases. Intervention(s): None. Main Outcome Measure(s): None. Result(s): There has been no systematic study of the long-term risk of cancer or other adverse outcomes in healthy egg donors. Conclusion(s): At present, potential egg donors cannot give truly informed consent because insufficient information exists about their long-term risks. (Fertil Steril (R) 2008;90:2016.e1-e5. (C) 2008 by American Society for Reproductive Medicine.)