Hierarchical Self-Assembled Photo-Responsive Tubisomes from a Cyclic Peptide-Bridged Amphiphilic Block Copolymer

被引：65

作者：

Yang, Jie ^{[1
]}

Song, Ji-Inn ^{[1
]}

Song, Qiao ^{[1
]}

Rho, Julia Y. ^{[1
]}

Mansfield, Edward D. H. ^{[1
]}

Hall, Stephen C. L. ^{[1
]}

Sambrook, Megan ^{[1
]}

Huang, Feihe ^{[2
]}

Perrier, Sebastien ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2020年 / 59卷 / 23期

基金：

欧洲研究理事会; 中国国家自然科学基金;

关键词：

drug loading; nanotubes; peptide-polymer conjugates; photo-responsive materials; tubisomes; POLYMER; NANOPARTICLES; NANOTUBES;

D O I：

10.1002/anie.201916111

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Typically, the morphologies of the self-assembled nanostructures from block copolymers are limited to spherical micelles, wormlike micelles and vesicles. Now, a new generation of materials with unique shape and structures, cylindrical soft matter particles (tubisomes), are obtained from the hierarchical self-assembly of cyclic peptide-bridged amphiphilic diblock copolymers. The capacity of obtained photo-responsive tubisomes as potential drug carriers is evaluated. The supramolecular tubisomes pave an alternative way for fabricating polymeric tubular structures, and will expand the toolbox for the rational design of functional hierarchical nanostructures.

引用

页码：8860 / 8863

页数：4

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