Costs and health-related quality of life of patients with cystic fibrosis and their carers in France

被引：34

作者：

Chevreul, Karine ^{[1
,2
,3
]}

Brigham, Karen Berg ^{[1
,4
]}

Michel, Morgane ^{[1
]}

Rault, Gilles ^{[5
]}

机构：

[1] URC Eco Ile France, DRCD, F-75004 Paris, France

[2] Univ Paris Diderot, ECEVE, UMRS 1123, F-75010 Paris, France

[3] INSERM, ECEVE, U1123, F-75010 Paris, France

[4] Univ Paris Est, F-94010 Creteil, France

[5] CRCM Roscoff, Ctr Perharidy, F-29684 Roscoff, France

来源：

JOURNAL OF CYSTIC FIBROSIS | 2015年 / 14卷 / 03期

关键词：

Cystic fibrosis; Health-related quality of life; Costs and cost analysis; Economic burden; LUNG-FUNCTION; CHILDREN; ILLNESS; EQ-5D; MULTICENTER; DISORDER; EUROQOL; STATE; AGE;

D O I：

10.1016/j.jcf.2014.11.006

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Background: Our goal was to provide data on the economic burden and health-related quality of life (HRQoL) associated with cystic fibrosis (CF) in France. Methods: A retrospective cross-sectional study was carried out on adults and children with CF, who completed an anonymous questionnaire regarding their socio-demographic characteristics, healthcare consumption and presence of a carer. Costs were calculated with a bottom-up approach, and HRQoL was assessed using EQ-5D. Results: 82 adults and 158 children were included. The total average annual cost of CF was (sic)29,746 per patient. Total costs were higher in adults than in children and increased with disease duration. The average utility was lower in adults (0.667 vs. 0.783 in children, p = 0.0015). The HRQoL of carers was also affected (0.742 and 0.765 for carers of adults and children with CF, respectively). Conclusions: Our study highlights the burden of CF in terms of costs and decreased HRQoL for both patients and carers. (C) 2014 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

引用

页码：384 / 391

页数：8

共 32 条

[1] Longitudinal association between lung function and health-related quality of life in cystic fibrosis [J].

Abbott, Janice ;

Hurley, Margaret A. ;

Morton, Alison M. ;

Conway, Steven P. .

THORAX, 2013, 68 (02) :149-154

[2]

[Anonymous], 2013, BILAN ACTIVITE 2012

[3]

[Anonymous], 2013, PREVALENCE MALADIES

[4]

Assurance Maladie, BAS MED INF TAR

[5] Quality of life and healthcare utilisation in cystic fibrosis: a multicentre study [J].

Bradley, Judy M. ;

Blume, Steven W. ;

Balp, Maria-Magdalena ;

Honeybourne, David ;

Elborn, J. Stuart .

EUROPEAN RESPIRATORY JOURNAL, 2013, 41 (03) :571-577

[6] Nationwide Trends in the Medical Care Costs of Privately Insured Patients With Cystic Fibrosis (CF), 2001-2007 [J].

Briesacher, Becky A. ;

Quittner, Alexandra L. ;

Fouayzi, Hassan ;

Zhang, Jie ;

Swensen, Andrine .

PEDIATRIC PULMONOLOGY, 2011, 46 (08) :770-776

[7]

CCEMG - EPPI-Centre Cost, CONVERTER V 1 2

[8]

Coldefy M, 2011, DISTANCES ACCES SOIN, V1, P1

[9] Resource Use, Costs, and Utility Estimates for Patients with Cystic Fibrosis with Mild Impairment in Lung Function: Analysis of Data Collected Alongside a 48-Week Multicenter Clinical Trial [J].

DeWitt, Esi Morgan ;

Grussemeyer, Chelsea A. ;

Friedman, Joelle Y. ;

Dinan, Michaela A. ;

Lin, Li ;

Schulman, Kevin A. ;

Reed, Shelby D. .

VALUE IN HEALTH, 2012, 15 (02) :277-283

[10] Outpatient medication costs of patients with cystic fibrosis in Germany [J].

Eidt-Koch D. ;

Wagner T.O.F. ;

Mittendorf T. ;

Graf Von Der Schulenburg J.-M. .

Applied Health Economics and Health Policy, 2010, 8 (2) :111-118

← 1 2 3 4 →