Opportunities for glyconanomaterials in personalized medicine

被引:16
|
作者
Reichardt, Niels-Christian [1 ,2 ]
Martin-Lomas, Manuel [1 ]
Penades, Soledad [1 ]
机构
[1] CIC biomaGUNE, Glycotechnol Lab, Paseo Miramon 182, San Sebastian 20009, Spain
[2] CIBER BBN, Paseo Miramon 182, San Sebastian 20009, Spain
关键词
MAGNETIC GLYCO-NANOPARTICLES; PROTEIN CORONA; GOLD NANOPARTICLES; DC-SIGN; CARBOHYDRATE ANTIGENS; TRANS-INFECTION; HYALURONIC-ACID; CELLULAR UPTAKE; CANCER; LECTIN;
D O I
10.1039/c6cc04445j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this feature article we discuss the particular relevance of glycans as components or targets of functionalized nanoparticles (NPs) for potential applications in personalized medicine but we will not enter into descriptions for their preparation. For a more general view covering the preparation and applications of glyconanomaterials the reader is referred to a number of recent reviews. The combination of glyco and nanotechnology is already providing promising new tools for more personalized solutions to diagnostics and therapy. Current applications relevant to personalized medicine include drug targeting, localized radiation therapy, imaging of glycan expression of cancer cells, point of care diagnostics, cancer vaccines, photodynamic therapy, biosensors, and glycoproteomics.
引用
收藏
页码:13430 / 13439
页数:10
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