InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

被引:1739
作者
Heberle, Henry [1 ]
Meirelles, Gabriela Vaz [2 ]
da Silva, Felipe R. [3 ]
Telles, Guilherme P. [4 ]
Minghim, Rosane [1 ]
机构
[1] Univ Sao Paulo, Inst Ciencias Matemat & Comp, Sao Carlos, SP, Brazil
[2] Lab Nacl Biociencias, Campinas, SP, Brazil
[3] Embrapa Informat Agr, Campinas, SP, Brazil
[4] Univ Estadual Campinas, Inst Comp, Campinas, SP, Brazil
关键词
Venn diagram; Edwards-Venn diagram; Interaction; Set-unions; SELECTION;
D O I
10.1186/s12859-015-0611-3
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Background: Set comparisons permeate a large number of data analysis workflows, in particular workflows in biological sciences. Venn diagrams are frequently employed for such analysis but current tools are limited. Results: We have developed InteractiVenn, a more flexible tool for interacting with Venn diagrams including up to six sets. It offers a clean interface for Venn diagram construction and enables analysis of set unions while preserving the shape of the diagram. Set unions are useful to reveal differences and similarities among sets and may be guided in our tool by a tree or by a list of set unions. The tool also allows obtaining subsets' elements, saving and loading sets for further analyses, and exporting the diagram in vector and image formats. InteractiVenn has been used to analyze two biological datasets, but it may serve set analysis in a broad range of domains. Conclusions: InteractiVenn allows set unions in Venn diagrams to be explored thoroughly, by consequence extending the ability to analyze combinations of sets with additional observations, yielded by novel interactions between joined sets. InteractiVenn is freely available online at: www.interactivenn.net.
引用
收藏
页数:7
相关论文
共 13 条
[1]   jvenn: an interactive Venn diagram viewer [J].
Bardou, Philippe ;
Mariette, Jerome ;
Escudie, Frederic ;
Djemiel, Christophe ;
Klopp, Christophe .
BMC BIOINFORMATICS, 2014, 15
[2]   A Critical Assessment of Feature Selection Methods for Biomarker Discovery in Clinical Proteomics [J].
Christin, Christin ;
Hoefsloot, Huub C. J. ;
Smilde, Age K. ;
Hoekman, B. ;
Suits, Frank ;
Bischoff, Rainer ;
Horvatovich, Peter .
MOLECULAR & CELLULAR PROTEOMICS, 2013, 12 (01) :263-276
[3]   The banana (Musa acuminata) genome and the evolution of monocotyledonous plants [J].
D'Hont, Angelique ;
Denoeud, France ;
Aury, Jean-Marc ;
Baurens, Franc-Christophe ;
Carreel, Francoise ;
Garsmeur, Olivier ;
Noel, Benjamin ;
Bocs, Stephanie ;
Droc, Gaetan ;
Rouard, Mathieu ;
Da Silva, Corinne ;
Jabbari, Kamel ;
Cardi, Celine ;
Poulain, Julie ;
Souquet, Marlene ;
Labadie, Karine ;
Jourda, Cyril ;
Lengelle, Juliette ;
Rodier-Goud, Marguerite ;
Alberti, Adriana ;
Bernard, Maria ;
Correa, Margot ;
Ayyampalayam, Saravanaraj ;
Mckain, Michael R. ;
Leebens-Mack, Jim ;
Burgess, Diane ;
Freeling, Mike ;
Mbeguie-A-Mbeguie, Didier ;
Chabannes, Matthieu ;
Wicker, Thomas ;
Panaud, Olivier ;
Barbosa, Jose ;
Hribova, Eva ;
Heslop-Harrison, Pat ;
Habas, Remy ;
Rivallan, Ronan ;
Francois, Philippe ;
Poiron, Claire ;
Kilian, Andrzej ;
Burthia, Dheema ;
Jenny, Christophe ;
Bakry, Frederic ;
Brown, Spencer ;
Guignon, Valentin ;
Kema, Gert ;
Dita, Miguel ;
Waalwijk, Cees ;
Joseph, Steeve ;
Dievart, Anne ;
Jaillon, Olivier .
NATURE, 2012, 488 (7410) :213-+
[4]   Gene selection for cancer classification using support vector machines [J].
Guyon, I ;
Weston, J ;
Barnhill, S ;
Vapnik, V .
MACHINE LEARNING, 2002, 46 (1-3) :389-422
[5]   BioVenn - a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams [J].
Hulsen, Tim ;
de Vlieg, Jacob ;
Alkema, Wynand .
BMC GENOMICS, 2008, 9 (1)
[6]  
Kawahara R, INTEGRATIVE ANAL SEL
[7]   Generalized Venn diagrams:: a new method of visualizing complex genetic set relations [J].
Kestler, HA ;
Müller, A ;
Gress, TM ;
Buchholz, M .
BIOINFORMATICS, 2005, 21 (08) :1592-1595
[8]   Identification of Differentially Expressed Proteins in Direct Expressed Prostatic Secretions of Men with Organ-confined Versus Extracapsular Prostate Cancer [J].
Kim, Yunee ;
Ignatchenko, Vladimir ;
Yao, Cindy Q. ;
Kalatskaya, Irina ;
Nyalwidhe, Julius O. ;
Lance, Raymond S. ;
Gramolini, Anthony O. ;
Troyer, Dean A. ;
Stein, Lincoln D. ;
Boutros, Paul C. ;
Medin, Jeffrey A. ;
Semmes, O. John ;
Drake, Richard R. ;
Kislinger, Thomas .
MOLECULAR & CELLULAR PROTEOMICS, 2012, 11 (12) :1870-1884
[9]   Uncovering Ecosystem Service Bundles through Social Preferences [J].
Martin-Lopez, Berta ;
Iniesta-Arandia, Irene ;
Garcia-Llorente, Marina ;
Palomo, Ignacio ;
Casado-Arzuaga, Izaskun ;
Garcia Del Amo, David ;
Gomez-Baggethun, Erik ;
Oteros-Rozas, Elisa ;
Palacios-Agundez, Igone ;
Willaarts, Barbara ;
Gonzalez, Jose A. ;
Santos-Martin, Fernando ;
Onaindia, Miren ;
Lopez-Santiago, Cesar ;
Montes, Carlos .
PLOS ONE, 2012, 7 (06)
[10]   On the beta-binomial model for analysis of spectral count data in label-free tandem mass spectrometry-based proteomics [J].
Pham, Thang V. ;
Piersma, Sander R. ;
Warmoes, Marc ;
Jimenez, Connie R. .
BIOINFORMATICS, 2010, 26 (03) :363-369