Linear IgA Disease: Clinical Presentation, Diagnosis, and Pathogenesis

被引：31
作者：
Venning, Vanessa A. [1 ]
机构：
[1] Churchill Hosp, Dept Dermatol, Oxford OX3 7LJ, England
来源：
DERMATOLOGIC CLINICS | 2011年 / 29卷 / 03期
关键词：
Linear IgA disease; LAD; Chronic bullous dermatosis of childhood; CBDC; CHRONIC BULLOUS DERMATOSIS; DERMATITIS-HERPETIFORMIS; BP180; MOLECULE; NC16A DOMAIN; CHILDHOOD; ADULTS; AUTOANTIBODIES; ASSOCIATION; ANTIBODIES; PATIENT;
D O I：
10.1016/j.det.2011.03.013
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Linear IgA disease is one of the rarer subepidermal blistering diseases. Linear IgA disease is a chronic, acquired, autoimmune blistering disease that is characterized by subepidermal blistering and linear deposition of IgA basement membrane antibodies. The disease affects both children and adults and, although there are some differences in their clinical presentations, there is considerable overlap with shared immunopathology and immunogenetics.
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页码：453 / +
页数：7
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