Histamine H3 receptor-mediated inhibition of noradrenaline release in the human brain

被引：30
作者：
Schlicker, E
Werthwein, S
Zentner, J
机构：
[1] Univ Bonn, Inst Pharmakol, D-53113 Bonn, Germany
[2] Univ Freiburg, Neurochirurg Klin, D-79106 Freiburg, Germany
来源：
FUNDAMENTAL & CLINICAL PHARMACOLOGY | 1999年 / 13卷 / 01期
关键词：
human cerebral cortex; human hippocampus; histamine H-3 receptors; noradrenaline release;
D O I：
10.1111/j.1472-8206.1999.tb00330.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Stimulation-evoked H-3-noradrenaline release in human cerebrocortical slices was inhibited by histamine (in a manner sensitive to clobenpropit) and by imetit, suggesting H-3 receptor-mediated inhibition of noradrenaline release in human brain. (C) Elsevier, Paris.
引用
收藏
页码：120 / 122
页数：3
相关论文
共 6 条
[1]   H-3-RECEPTORS CONTROL HISTAMINE-RELEASE IN HUMAN-BRAIN [J].
ARRANG, JM ;
DEVAUX, B ;
CHODKIEWICZ, JP ;
SCHWARTZ, JC .
JOURNAL OF NEUROCHEMISTRY, 1988, 51 (01) :105-108
[2]  
Hill SJ, 1997, PHARMACOL REV, V49, P253
[3]   Therapeutic potential histamine H3 receptor agonists and antagonists [J].
Leurs, R ;
Blandina, P ;
Tedford, C ;
Timmerman, H .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1998, 19 (05) :177-183
[4]   INHIBITION OF NORADRENALINE RELEASE FROM THE SYMPATHETIC-NERVES OF THE HUMAN SAPHENOUS-VEIN BY PRESYNAPTIC HISTAMINE H-3 RECEPTORS [J].
MOLDERINGS, GJ ;
WEISSENBORN, G ;
SCHLICKER, E ;
LIKUNGU, J ;
GOTHERT, M .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1992, 346 (01) :46-50
[5]  
SCHLICKER E, 1992, N-S ARCH PHARMACOL, V345, P489
[6]   H2 receptor-mediated facilitation and H3 receptor-mediated inhibition of noradrenaline release in the guinea-pig brain [J].
Timm, J ;
Marr, I ;
Werthwein, S ;
Elz, S ;
Schunack, W ;
Schlicker, E .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 357 (03) :232-239
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