CD146: the unveiling of a pro-angiogenic netrin receptor

被引：11
|
作者：
St Croix, Brad [1 ]
机构：
[1] NCI, Tumor Angiogenesis Sect, Mouse Canc Genet Program, NIH, Frederick, MD 21702 USA
来源：
CELL RESEARCH | 2015年 / 25卷 / 05期
关键词：
D O I：
10.1038/cr.2015.42
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Netrin-1, a classic neuronal guidance cue, can promote angiogenesis under certain developmental and pathological conditions, but key receptors on vascular endothelium have remained elusive. A recent study published in Cell Research by Tu et al. reveals that CD146, an endothelial receptor of the immunoglobulin superfamily, binds netrin-1 with high affinity and may play an important role in regulating angiogenesis.
引用
收藏
页码：533 / 534
页数：2
相关论文
共 50 条
  • [1] CD146: the unveiling of a pro-angiogenic netrin receptor
    Brad St Croix
    Cell Research, 2015, 25 : 533 - 534
  • [2] Netrin-1 role in angiogenesis To be or not to be a pro-angiogenic factor?
    Castets, Marie
    Mehlen, Patrick
    CELL CYCLE, 2010, 9 (08) : 1466 - 1471
  • [3] CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development
    Tao Tu
    Chunxia Zhang
    Huiwen Yan
    Yongting Luo
    Ruirui Kong
    Pushuai Wen
    Zhongde Ye
    Jianan Chen
    Jing Feng
    Feng Liu
    Jane Y Wu
    Xiyun Yan
    Cell Research, 2015, 25 : 275 - 287
  • [4] CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development
    Tu, Tao
    Zhang, Chunxia
    Yan, Huiwen
    Luo, Yongting
    Kong, Ruirui
    Wen, Pushuai
    Ye, Zhongde
    Chen, Jianan
    Feng, Jing
    Liu, Feng
    Wu, Jane Y.
    Yan, Xiyun
    CELL RESEARCH, 2015, 25 (03) : 275 - 287
  • [5] CD146/sCD146 in the Pathogenesis and Monitoring of Angiogenic and Inflammatory Diseases
    Heim, Xavier
    Joshkon, Ahmad
    Bermudez, Julien
    Bachelier, Richard
    Dubrou, Clea
    Boucraut, Jose
    Foucault-Bertaud, Alexandrine
    Leroyer, Aurelie S.
    Dignat-George, Francoise
    Blot-Chabaud, Marcel
    Bardin, Nathalie
    BIOMEDICINES, 2020, 8 (12) : 1 - 13
  • [6] soluble CD146: A new angiogenic factor involved in physiopathology
    Harhouri, Karim
    Bardin, Nathalie
    Dignat-George, Francoise
    Blot-Chabaud, Marcel
    THROMBOSIS RESEARCH, 2012, 130 : S108 - S108
  • [7] Netrin-4 Acts as a Pro-angiogenic Factor during Zebrafish Development
    Lambert, Elise
    Coissieux, Marie-May
    Laudet, Vincent
    Mehlen, Patrick
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (06) : 3987 - 3999
  • [8] Pro-angiogenic bacteria in the gut
    Christina Tobin Kåhrström
    Nature Reviews Microbiology, 2012, 10 (5) : 310 - 310
  • [9] Nicotine: A pro-angiogenic factor
    Costa, F.
    Soares, R.
    LIFE SCIENCES, 2009, 84 (23-24) : 785 - 790
  • [10] Pro-angiogenic gene therapy
    Yla-Herttuala, S.
    JOURNAL OF VASCULAR RESEARCH, 2011, 48 : 49 - 49
12345