Towards broadly protective polyvalent vaccines against hand, foot and mouth disease

被引：27
作者：
Liu, Qingwei [1 ]
Tong, Xin [2 ]
Huang, Zhong [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Pasteur Shanghai, Vaccine Res Ctr,Key Lab Mol Virol & Immunol, Shanghai 200031, Peoples R China
[2] Shanghai Zerun Biotechnol Co Ltd, Shanghai 201203, Peoples R China
来源：
MICROBES AND INFECTION | 2015年 / 17卷 / 02期
关键词：
Hand; foot; and mouth disease; Enterovirus; 71; Coxsackievirus A16; Polyvalent vaccine; VIRUS-LIKE PARTICLES; ENTEROVIRUS; 71; VACCINE; NEUTRALIZING LINEAR EPITOPES; COXSACKIEVIRUS A16; LETHAL ENTEROVIRUS-71; CYNOMOLGUS MONKEYS; IMMUNE-RESPONSES; SOUTHERN CHINA; EXPRESSING VP1; NEWBORN MICE;
D O I：
10.1016/j.micinf.2014.11.004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Hand, foot, and mouth disease (HFMD) caused by multiple enterovirus infections is a serious health threat to children in the Asia-Pacific region. This article reviews progresses in the development of vaccines for HFMD and discusses the need for polyvalent HFMD vaccines for conferring broad-spectrum protection. (C) 2014 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：155 / 162
页数：8
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