Gemini Surfactants Templated Mesoporous Silica Microparticles: from Solid to Hollow Mesoporous Spheres

被引：11
作者：
Li, Min
Zhang, Chun [1 ]
Yang, Xiangliang
机构：
[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Wuhan 430074, Hubei, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2017年 / 35卷 / 11期
基金：
中国国家自然科学基金;
关键词：
mesoporous silica microparticles; gemini surfactant; drug delivery system; doxorubicin; DRUG-DELIVERY; CONTROLLED-RELEASE; NANOPARTICLES; MCM-41; ADSORPTION; FUNCTIONALIZATION; MICROCAPSULES; FABRICATION; MORPHOLOGY; SBA-15;
D O I：
10.1002/cjoc.201700277
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We synthesized a series of mesoporous silica microparticles (MSs) using cationic gemini surfactants C14-2-n (n = 2, 6, 10, 14) as templates. The porous structures and pore size of these MSs can be tuned by varying the length of alkyl chain in gemini surfactant templates. These MSs showed effective doxorubicin (DOX) loading and a pH-responsive drug release characteristics. These results indicate that the MSs, especially the hollow mesoporous silica nanoparticles, have great potential for biomedical applications.
引用
收藏
页码：1706 / 1710
页数：5
相关论文
共 35 条
[1]   Synthesis of mesoporous MSU-X materials using inexpensive silica sources [J].
Boissière, C ;
Larbot, A ;
Prouzet, E .
CHEMISTRY OF MATERIALS, 2000, 12 (07) :1937-1940
[2]   A study of the assembly mechanism of the mesoporous MSU-X silica two-step synthesis [J].
Boissière, C ;
Larbot, A ;
Bourgaux, C ;
Prouzet, E ;
Bunton, CA .
CHEMISTRY OF MATERIALS, 2001, 13 (10) :3580-3586
[3]   Dilute solution routes to various controllable morphologies of MCM-41 silica with a basic medium [J].
Cai, Q ;
Luo, ZS ;
Pang, WQ ;
Fan, YW ;
Chen, XH ;
Cui, FZ .
CHEMISTRY OF MATERIALS, 2001, 13 (02) :258-263
[4]   Mesopore size and surface area calculations for hexagonal mesophases (types MCM41, FSM-16, etc.) using low-angle XRD and adsorption data [J].
Fenelonov, VB ;
Romannikov, VN ;
Derevyankin, AL .
MICROPOROUS AND MESOPOROUS MATERIALS, 1999, 28 (01) :57-72
[5]   Mixed anionic surfactant-templated mesoporous silica nanoparticles for fluorescence detection of Fe3+ [J].
Gai, Fangyuan ;
Zhou, Tianlei ;
Chu, Guang ;
Li, Ye ;
Liu, Yunling ;
Huo, Qisheng ;
Akhtar, Farid .
DALTON TRANSACTIONS, 2016, 45 (02) :508-514
[6]   Controlling the morphology of mesostructured silicas by pseudomorphic transformation: A route towards applications [J].
Galarneau, Anne ;
Iapichella, Julien ;
Bonhomme, Karine ;
Di Renzo, Francesco ;
Kooyman, Patricia ;
Terasaki, Osamu ;
Fajula, Francois .
ADVANCED FUNCTIONAL MATERIALS, 2006, 16 (13) :1657-1667
[7]   A magnetic, reversible pH-responsive nanogated ensemble based on Fe3O4 nanoparticles-capped mesoporous silica [J].
Gan, Qi ;
Lu, Xunyu ;
Yuan, Yuan ;
Qian, Jiangchao ;
Zhou, Huanjun ;
Lu, Xun ;
Shi, Jianlin ;
Liu, Changsheng .
BIOMATERIALS, 2011, 32 (07) :1932-1942
[8]   Novel pathways for the preparation of mesoporous MCM-41 materials:: control of porosity and morphology [J].
Grün, M ;
Unger, KK ;
Matsumoto, A ;
Tsutsumi, K .
MICROPOROUS AND MESOPOROUS MATERIALS, 1999, 27 (2-3) :207-216
[9]   Cubic mesoporous silica with tailored large pores [J].
Hamoudi, S ;
Belkacemi, K .
JOURNAL OF POROUS MATERIALS, 2004, 11 (01) :47-54
[10]   Evolution of Packing Parameters in the Structural Changes of Silica Mesoporous Crystals: Cage-Type, 2D Cylindrical, Bicontinuous Diamond and Gyroid, and Lamellar [J].
Han, Lu ;
Miyasaka, Keiichi ;
Terasaki, Osamu ;
Che, Shunai .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (30) :11524-11533
1234