Gadolinium-doped Cu-In-Zn-S quantum dots: one-pot aqueous synthesis and multimodal bioimaging

被引：0

作者：

Zhang, L. ^{[1
]}

Wan, Y. ^{[1
]}

Xue, J. ^{[1
]}

Duan, W. ^{[1
]}

Chen, D. ^{[1
]}

Wu, Y. ^{[1
]}

Wang, J. ^{[1
]}

Xu, D. ^{[1
]}

Liu, D. ^{[2
]}

机构：

[1] Qiqihar Med Univ, Coll Med Technol, Qiqihar 161006, Heilongjiang, Peoples R China

[2] Qiqihar Univ, Commun & Elect Engn Inst, Qiqihar 161006, Heilongjiang, Peoples R China

来源：

JOURNAL OF OVONIC RESEARCH | 2021年 / 17卷 / 05期

关键词：

GCIZS QDs; gadolinium doped; multimodality imaging; GSH capped; HIGHLY LUMINESCENT; FACILE SYNTHESIS; NANOCRYSTALS; QDS;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We report a one-pot method to directly synthesize magnetic resonance/fluorescence multimodal imaging gadolinium-doped Cu-In-Zn-S quantum dots(GCIZS QDs) in aqueous media by using bio-compatible glutathione (GSH) as capping ligand and stabilizer. The optical features and structure of the GCIZS QDs have been characterized by UV-vis and fluorescence spectroscopy, XRD, TEM, and FT-IR. As a result, The GCIZS QDs possessed a strong fluorescence and r(1) value of 4.015 mM(-1)s(-1) at the Cu/Gd ratio of 1/2. Furthermore, the GCIZS QDs were good water solubility and less cytotoxic up to 250 mu g/mL in HUVEC cells. The red emission GCIZS QDs from the MDA-MB-231cells was clearly observed under microscope. It indicated that the GCIZS QDs present great potential as magnetic resonance / fluorescence multimodal imaging contrast agents for biological labels.

引用

页码：471 / 478

页数：8

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