free boundary problem;
tumor growth;
global solution;
existence;
D O I:
暂无
中图分类号:
O29 [应用数学];
学科分类号:
070104 ;
摘要:
In this paper we study a free boundary problem for a reaction- diffusion equation modeling the growth of necrotic tumors. We first reduce this problem into an equivalent initial boundary value problem for a nonlinear parabolic equation on a fixed domain. This parabolic equation is strongly singular in the sense that not only it contains a discontinuous nonlinear function of the unknown function, but also all its coefficients are discontinuous nonlinear functionals of the unknown function. We use the approximation method and the Schauder fixed point theorem combined with L-p estimates to prove the existence of a global solution.