Protein-protein interaction networks and biology - what's the connection?

被引：140
作者：
Hakes, Luke [1 ]
Pinney, John W. [1 ]
Robertson, David L. [1 ]
Lovell, Simon C. [1 ]
机构：
[1] Univ Manchester, Fac Life Sci, Manchester M13 9PT, Lancs, England
来源：
NATURE BIOTECHNOLOGY | 2008年 / 26卷 / 01期
基金：
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词：
D O I：
10.1038/nbt0108-69
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Analysis of protein-protein interaction networks is an increasingly popular means to infer biological insight, but is close enough attention being paid to data handling protocols and the degree of bias in the data?.
引用
收藏
页码：69 / 72
页数：4
相关论文
共 35 条
  • [1] LGL: Creating a map of protein function with an algorithm for visualizing very large biological networks
    Adai, AT
    Date, SV
    Wieland, S
    Marcotte, EM
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2004, 340 (01) : 179 - 190
  • [2] Error and attack tolerance of complex networks
    Albert, R
    Jeong, H
    Barabási, AL
    [J]. NATURE, 2000, 406 (6794) : 378 - 382
  • [3] Potential artefacts in protein-interaction networks
    Aloy, P
    Russell, RB
    [J]. FEBS LETTERS, 2002, 530 (1-3) : 253 - 254
  • [4] [Anonymous], NETWORK ANAL
  • [5] Network biology:: Understanding the cell's functional organization
    Barabási, AL
    Oltvai, ZN
    [J]. NATURE REVIEWS GENETICS, 2004, 5 (02) : 101 - U15
  • [6] Emergence of scaling in random networks
    Barabási, AL
    Albert, R
    [J]. SCIENCE, 1999, 286 (5439) : 509 - 512
  • [7] Still stratus not altocumulus: Further evidence against the date/party hub distinction
    Batada, Nizar N.
    Reguly, Teresa
    Breitkreutz, Ashton
    Boucher, Lorrie
    Breitkreutz, Bobby-Joe
    Hurst, Laurence D.
    Tyers, Mike
    [J]. PLOS BIOLOGY, 2007, 5 (06) : 1202 - 1206
  • [8] Evolutionary and physiological importance of hub proteins
    Batada, Nizar N.
    Hurst, Laurence D.
    Tyers, Mike
    [J]. PLOS COMPUTATIONAL BIOLOGY, 2006, 2 (07) : 748 - 756
  • [9] Stratus not altocumulus: A new view of the yeast protein interaction network
    Batada, Nizar N.
    Reguly, Teresa
    Breitkreutz, Ashton
    Boucher, Lorrie
    Breitkreutz, Bobby-Joe
    Hurst, Laurence D.
    Tyers, Mike
    [J]. PLOS BIOLOGY, 2006, 4 (10) : 1720 - 1731
  • [10] Structure and evolution of protein interaction networks:: a statistical model for link dynamics and gene duplications -: art. no. 51
    Berg, J
    Lässig, M
    Wagner, A
    [J]. BMC EVOLUTIONARY BIOLOGY, 2004, 4 (1)
1234