Variable oncogene promoter activity of human papillomavirus type 16 cervical cancer isolates from Australia

被引：14
作者：
Watts, KJ [1 ]
Thompson, CH [1 ]
Cossart, YE [1 ]
Rose, BR [1 ]
机构：
[1] Univ Sydney, Dept Infect Dis, Sydney, NSW 2006, Australia
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2001年 / 39卷 / 05期
关键词：
D O I：
10.1128/JCM.39.5.2009-2014.2001
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The functional significance of sequence variation within the upstream regulatory region (URR) of six human papillomavirus type 16 (HPV16) cervical cancer isolates from Australia was investigated. Specific changes in transcription factor binding sites leading to increased promoter activity map explain the transforming ability of some episomal HPV16 isolates.
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页码：2009 / 2014
页数：6
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