Bufadienolides and their antitumor activity

被引:135
作者
Gao, Huimin [1 ]
Popescu, Ruxandra [2 ]
Kopp, Brigitte [2 ]
Wang, Zhimin [1 ]
机构
[1] China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing 100700, Peoples R China
[2] Univ Vienna, Dept Pharmacognosy, A-1090 Vienna, Austria
关键词
PERFORMANCE LIQUID-CHROMATOGRAPHY; ENDOGENOUS CARDIAC-GLYCOSIDES; BUFALIN-INDUCED APOPTOSIS; CELL-SUSPENSION CULTURES; SODIUM-PUMP INHIBITORS; RED-BELLIED TOADS; CYTOTOXIC BUFADIENOLIDES; CARDIOTONIC STEROIDS; CHINESE MEDICINE; RAT PLASMA;
D O I
10.1039/c0np00032a
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Since 1998, a great number of bufadienolides have been reported from plants, animals and plant cell suspensions, as well as from fungi and bacteria cultures. This review summarizes both new bufadienolides and those obtained from new sources, together with data regarding the antitumor activity of bufadienolide derivatives.
引用
收藏
页码:953 / 969
页数:17
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