Scrub Typhus With Secondary Hemophagocytic Lymphohistiocytosis

被引:1
作者
Jayachandran, Akshaya [1 ]
Sundaresan, Durgadevi [1 ]
Pannu, Ashok Kumar [1 ]
Ahluwalia, Jasmina [1 ]
Chinnadurai, Krishna Kumar [1 ]
Saroch, Atul [1 ]
机构
[1] PGIMER, Dept Internal Med, Chandigarh, India
关键词
scrub typhus; infection; HLH;
D O I
10.1097/IPC.0000000000001008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Scrub typhus is a rickettsial disease transmitted to humans by arthropods, via the bite of larval mites (chiggers). A young man, aged 18 years admitted with the fever of 5 days and altered sensorium for 1 day. The patient was evaluated for tropical illness with encephalopathy and multiorgan dysfunction syndrome. Patient serology was positive for scrub typhus and fulfill requisite criteria (hemophagocytic lymphohistiocytosis [HLH]-2004) for secondary HLH. He was managed as scrub typhus with secondary HLH and was given dexamethasone 4 mg three times a day. Patient condition improved and discharged with normal vital.
引用
收藏
页码:E443 / E445
页数:3
相关论文
共 11 条
[1]  
Crecelius Elena M, 2020, J Spec Oper Med, V20, P120, DOI 10.55460/WCLB-0NKA
[2]  
He Shijun, 2014, Zhonghua Er Ke Za Zhi, V52, P683
[3]   HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis [J].
Henter, Jan-Inge ;
Horne, AnnaCarin ;
Arico, Maurizio ;
Egeler, R. Maarten ;
Filipovich, Alexandra H. ;
Imashuku, Shinsaku ;
Ladisch, Stephan ;
McClain, Ken ;
Webb, David ;
Winiarski, Jacek ;
Janka, Gritta .
PEDIATRIC BLOOD & CANCER, 2007, 48 (02) :124-131
[4]   Familial and Acquired Hemophagocytic Lymphohistiocytosis [J].
Janka, G. E. .
ANNUAL REVIEW OF MEDICINE, VOL 63, 2012, 63 :233-246
[5]   Scrub typhus associated with hemophagocytic lymphohistiocytosis: A report of six pediatric patients [J].
Jin, Yingkang ;
Huang, Li ;
Fan, Huifeng ;
Lu, Gen ;
Xu, Yi ;
Wu, Zhiyuan .
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2016, 12 (04) :2729-2734
[6]   Risk Factors Leading to Fatal Outcome in Scrub Typhus Patients [J].
Lee, Chang-Seop ;
Hwang, Jeong-Hwan ;
Lee, Heung-Bum ;
Kwon, Keun-Sang .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2009, 81 (03) :484-488
[7]   Misdiagnosis of scrub typhus complicated by hemophagocytic syndrome [J].
Lin, Miaomiao ;
Huang, Airong ;
Zheng, Xiang ;
Ge, Lisha ;
He, Shijun .
BMC PEDIATRICS, 2019, 19 (1)
[8]   Hemophagocytic Lymphohistiocytosis Associated with Scrub Typhus: Systematic Review and Comparison between Pediatric and Adult Cases [J].
Naoi, Tameto ;
Morita, Mitsuya ;
Kawakami, Tadataka ;
Fujimoto, Shigeru .
TROPICAL MEDICINE AND INFECTIOUS DISEASE, 2018, 3 (01)
[9]   Clinical manifestations of scrub typhus [J].
Rajapakse, Senaka ;
Weeratunga, Praveen ;
Sivayoganathan, Sriharan ;
Fernando, Sumadhya Deepika .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2017, 111 (02) :43-54
[10]   Hemophagocytosis in scrub typhus [J].
Valsalan, R. ;
Kosaraju, K. ;
Sohanlal, T. ;
Kumar, Prem P. S. .
JOURNAL OF POSTGRADUATE MEDICINE, 2010, 56 (04) :301-302