Identification of an insertion sequence located in a region encoding virulence factors of Streptococcus pyogenes

被引：19

作者：

Berge, A ^{[1
]}

Rasmussen, M ^{[1
]}

Björck, L ^{[1
]}

机构：

[1] Lund Univ, Sect Mol Pathogenesis, Dept Cell & Mol Biol, S-22100 Lund, Sweden

来源：

INFECTION AND IMMUNITY | 1998年 / 66卷 / 07期

关键词：

D O I：

10.1128/IAI.66.7.3449-3453.1998

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An insertion sequence, IS1562, was identified in a Streptococcus pyogenes strain of the clinically important M1 serotype. IS1562 is located in the mga regulon between the genes coding for the M protein and the C5a peptidase, both important virulence factors. The same or similar insertion sequences were found in most S. pyogenes strains, but the chromosomal location differed among isolates.

引用

页码：3449 / 3453

页数：5

共 35 条

[1] Protein SIC, a novel extracellular protein of Streptococcus pyogenes interfering with complement function [J].

Akesson, P ;

Sjoholm, AG ;

Bjorck, L .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (02) :1081-1088

[2] DISSEMINATION AMONG STAPHYLOCOCCI OF DNA-SEQUENCES ASSOCIATED WITH METHICILLIN RESISTANCE [J].

ARCHER, GL ;

NIEMEYER, DM ;

THANASSI, JA ;

PUCCI, MJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (03) :447-454

[3] Characterization of IS1272, an insertion sequence-like element from Staphylococcus haemolyticus [J].

Archer, GL ;

Thanassi, JA ;

Niemeyer, DM ;

Pucci, MJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (04) :924-929

[4]

CAMPBELL A, 1977, DNA INSERTION ELEMEN, P15

[5] IDENTIFICATION OF A GENE THAT REGULATES EXPRESSION OF M-PROTEIN, THE MAJOR VIRULENCE DETERMINANT OF GROUP-A STREPTOCOCCI [J].

CAPARON, MG ;

SCOTT, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (23) :8677-8681

[6] TRANSLATIONAL FRAMESHIFTING IN THE CONTROL OF TRANSPOSITION IN BACTERIA [J].

CHANDLER, M ;

FAYET, O .

MOLECULAR MICROBIOLOGY, 1993, 7 (04) :497-503

[7]

CHEN CC, 1990, J BIOL CHEM, V265, P3161

[8]

CUNNINGHAM RP, 1994, ANN NY ACAD SCI, V29, P215

[9] ZINC FINGERS - GILT BY ASSOCIATION [J].

EVANS, RM ;

HOLLENBERG, SM .

CELL, 1988, 52 (01) :1-3

[10] STREPTOCOCCAL M-PROTEIN - MOLECULAR DESIGN AND BIOLOGICAL BEHAVIOR [J].

FISCHETTI, VA .

CLINICAL MICROBIOLOGY REVIEWS, 1989, 2 (03) :285-314

← 1 2 3 4 →